Anti-Glycophorin A Antibody | Boster A02184 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-Glycophorin A Antibody

catalog :

A02184

quantity :

100 ug/200 ul

price :

290 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry

product information

sku :

A02184

name :

Anti-Glycophorin A Antibody

price :

290 USD

immunogen :

Synthetic peptide with sequence C-SVEIENPETSDQ, corresponding to the C Terminus of the protein sequence.

form :

Liquid

host :

Goat

contents :

Each vial contains the specific antibody at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% BSA.

purification :

Immunogen Affinity Purified

clonality :

Polyclonal

description :

Goat Anti-Glycophorin A Antibody for GYPA detection tested with WB, IHC in Human.

size :

100 ug/200 ul

reactivity :

Human

applications :

IHC; WB

background :

Glycophorin A (MNS blood group), also known as GYPA, is a protein which in humans is encoded by the GYPA gene. GYPA has also recently been designated CD235a (cluster of differentiation 235a). Glycophorins A (GYPA; this protein) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB.

gene full name :

Glycophorin-A

gene name :

GYPA

protein function :

Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV).

subcellular localization :

Cell membrane ; Single-pass type I membrane protein . Appears to be colocalized with SLC4A1.

synonyms :

Glycophorin-A;MN sialoglycoprotein;PAS-2;Sialoglycoprotein alpha;CD235a;GYPA;GPA;

uniprot id :

P02724