Anti-Biglycan BGN Antibody | Boster A02090 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-Biglycan BGN Antibody

catalog :

A02090

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

polyclonal

reactivity :

human

application :

western blot, immunohistochemistry, immunoprecipitation, flow cytometry

product information

SKU :

A02090

Product Name :

Anti-Biglycan BGN Antibody

Size :

100 ul

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human, Mouse

Application(s) :

WB, IHC, Flow Cytometry, IP

Application Details :

WB:1:500-1:1000 IHC:1:50-1:200 FC:1:50-1:100

Description :

Boster Bio Anti-Biglycan BGN Antibody catalog # A02090. Tested in Flow Cytometry, IP, IHC, WB applications. This antibody reacts with Human, Mouse.

Gene Name :

BGN

Uniprot ID :

P21810

Form :

Liquid

Contents :

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification :

ProA affinity purified

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Interleukin-37

Synonyms :

Interleukin-37; FIL1 zeta; IL-1X; Interleukin-1 family member 7; IL-1F7; Interleukin-1 homolog 4; IL-1H; IL-1H4; Interleukin-1 zeta; IL-1 zeta; Interleukin-1-related protein; IL-1RP1; Interleukin-23; IL-37; IL37; FIL1Z, IL1F7, IL1H4, IL1RP1;

Protein Name :

Interleukin-37

Molecular Weight :

24126 MW

Protein Function :

Suppressor of innate inflammatory and immune responses involved in curbing excessive inflammation. This function requires SMAD3. Suppresses, or reduces, proinflammatory cytokine production, including IL1A and IL6, as well as CCL12, CSF1, CSF2, CXCL13, IL1B, IL23A and IL1RN, but spares anti-inflammatory cytokines. Inhibits dendritic cell activation.

Subcellular Localization :

Cytoplasm, cytosol

Tissue Specificity :

In general, low constitutive expression, if any, in healthy tissues; high expression in inflammatory counterparts, including in synovial tissues from individuals with active rheumatoid arthritis. Isoform A, isoform B and isoform C are expressed in testis, colon, placenta, lung and lymph node. Isoform D and isoform E were found only in testis and bone marrow. Whereas only isoform A is found in brain, only isoform B in kidney and only isoform C in heart.