Anti-Gab1(Phospho-Tyr627) Antibody | Boster A01989 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Gab1(Phospho-Tyr627) Antibody

catalog :

A01989

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunocytochemistry

product information

sku :

A01989

status :

Enabled

name :

Anti-Gab1(Phospho-Tyr627) Antibody

category name :

Primary Antibodies, Polyclonal Antibodies, IHC ICC IF Antibodies

gene name :

GAB1

price various sizes :

5ul sample size / $40 100ul / $299 100ul+Free HRP Secondary BA1054 / $299 100ul+Free Biotin Secondary BA1003 / $299

clonality :

Polyclonal

concentration :

1.02 mg/mL by UV absorbance at 280 nm

conjugate :

contents :

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

description :

Polyclonal antibody for GAB1 detection. Host: Rabbit.Size: 100ul. Tested applications: IF. Reactive species: Human. GAB1 information: Molecular Weight: 76616 MW; .

short description :

Rabbit Polyclonal Antibody for Gab1(Phospho-Tyr627) (GAB1) detection.tested for IF, IHC, WB in Human, Mouse.

size :

100 ul

sample size available :

5ul, free with shipping charge

uniprot id :

Q13480

host :

Rabbit

immunogen :

Peptide sequence around phosphorylation site of tyrosine 627 (V-E-Y(p)-L-D) derived from Human Gab1.

form :

Liquid

purification :

Immunogen affinity purified

storage :

Store at -20 C for one year, at 4 C for one month. We suggest the antibody be aliquotted into small vials and stored frozen at -20 C upon receiving. Avoid repeated freezing and thawing.

application details :

WB, 1:500-1:1000. Immunofluorescence, 1:100-1:200

applications :

IF, WB

reactivity :

Human, Mouse

image labels :

Western blot analysis of GAB1 expression in MCF7 lysate (lane 1), GAB1 Protein (lane 2) and GST protein (lane 3). GAB1 at 130KD was detected using rabbit anti-GAB1 polyclonal antibody (Catalog # A01989) at 1ug/mL. The blot was developed using chemiluminescence (ECL) method (Catalog # EK1002). Western blot analysis of extracts from 293 cells untreated or treated with EGF using Gab1(Phospho-Tyr627) antibody A01989. Immunofluorescence staining of methanol-fixed Hela cells using Gab1(Phospho-Tyr627) antibody A01989.

background :

GRB2-associated-binding protein 1 is a protein that in humans is encoded by the GAB1 gene. It is mapped to 4q31.21. The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.

competitor equivalent skus :

sc 86134 sc 86133

research category :

Adapters, Apoptosis, Cancer, Cell Biology, Cell Cycle, Cell Differentiation, Cytoplasmic, Intracellular, Kinases, Mapk Pathway, Protein Phosphorylation, Ser / Thr Kinases, Signal Transduction

synonyms :

GRB2-associated-binding protein 1;GRB2-associated binder 1;Growth factor receptor bound protein 2-associated protein 1;GAB1;

gene full name :

GRB2-associated-binding protein 1

molecular weight :

76616 MW

protein function :

Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR).

last modified :

1/28/19 19:39