Anti-Tryptophan Hydroxylase/TPH1 Antibody Picoband™ | Boster A01626-1 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Tryptophan Hydroxylase/TPH1 Antibody Picoband™

catalog :

A01626-1

quantity :

100µg/vial

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA

product information

SKU :

A01626-1

Product Name :

Anti-Tryptophan Hydroxylase/TPH1 Antibody Picoband™

Size :

100µg/vial

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

ELISA, WB

Application Details :

Western blot, 0.1-0.5µg/ml. Direct ELISA, 0.1-0.5µg/ml.

Description :

Boster Bio Anti-Tryptophan Hydroxylase/TPH1 Antibody Picoband™ catalog # A01626-1. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Gene Name :

TPH1

Uniprot ID :

P17752

Immunogen :

E. coli-derived human Tryptophan Hydroxylase recombinant protein (Position: M1-K111).

Form :

Lyophilized

Contents :

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na 2 HPO 4 , 0.05mg NaN 3 .

Cross-reactivity :

No cross reactivity with other proteins.

Storage :

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Gene Full Name :

tryptophan hydroxylase 1

Synonyms :

Tryptophan 5-hydroxylase 1; Tryptophan 5-monooxygenase 1; TPH1; TPH; TPRH; TRPH

Tissue Specificity :

Isoform 2 seems to be less widely expressed than isoform 1.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.

Background :

Tryptophan hydroxylase 1 (TPH1) is an isoenzyme of tryptophan hydroxylase which in humans is encoded by the TPH1 gene. This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.

Research Category :

Amino Acid Metabolism, Amino Acids, Cancer, Cancer Metabolism, Endocrine Metabolism, Energy Metabolism, Energy Transfer Pathways, Hormone Biosynthesis, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Neuroscience, Neurotransmitter, Pathways And Processes, Signal Transduction