Anti-BIM(Ab-69) Antibody | Boster A01552-1 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-BIM(Ab-69) Antibody

catalog :

A01552-1

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

product information

sku :

A01552-1

status :

Enabled

name :

Anti-BIM(Ab-69) Antibody

category name :

Primary Antibodies, Polyclonal Antibodies, IHC ICC IF Antibodies

gene name :

BCL2L11

price various sizes :

5ul sample size / $40 100ul / $299 100ul+Free HRP Secondary BA1054 / $299 100ul+Free Biotin Secondary BA1003 / $299

clonality :

Polyclonal

concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

conjugate :

contents :

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

description :

Polyclonal antibody for BIM/BCL2L11 detection. Host: Rabbit.Size: 100ul. Tested applications: IHC. Reactive species: Human. BIM/BCL2L11 information: Molecular Weight: 22171 MW; Subcellular Localization: Endomembrane system ; Peripheral membrane protein . Associated with intracytoplasmic membranes; Tissue Specificity: Isoform BimEL, isoform BimL and isoform BimS are the predominant isoforms and are ubiquitously expressed with a tissue-specific variation. Isoform Bim-gamma is most abundantly expressed in small intestine and colon, and in lower levels in spleen, prostate, testis, heart, liver and kidney.

short description :

Rabbit Polyclonal Antibody for BIM(Ab-69) (BCL2L11) detection. Tested with WB, IHC in Human, Mouse, Rat.

size :

100 ul

sample size available :

5ul, free with shipping charge

uniprot id :

O43521

host :

Rabbit

immunogen :

Peptide sequence around aa.67~71 (P-A-S-P-G) derived from Human BIM.

form :

Liquid

purification :

Immunogen affinity purified

storage :

Store at -20 C for one year, at 4 C for one month. We suggest the antibody be aliquotted into small vials and stored frozen at -20 C upon receiving. Avoid repeated freezing and thawing.

application details :

WB, 1:500-1:1000. IHC, 1:50-1:100.

applications :

IHC, WB

reactivity :

Human, Mouse, Rat

image labels :

Western blot analysis of extracts from Hela cells using BIM(Ab-69) antibody A01552-1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using BIM(Ab-69) antibody A01552-1(left) or the same antibody preincubated with blocking peptide(right).

competitor equivalent skus :

sc 27985 sc 27982 sc 8265 sc 8267 sc 374358 sc 11425 sc 31687 sc 130511

research category :

Alzheimer'S Disease, Apoptosis, Apoptotic Markers, Associated Proteins, Cancer, Cell Biology, Cell Death, Immunology, Innate Immunity, Intracellular, Invasion/Microenvironment, Macrophage / Inflamm., Mapk Pathway, Metabolism, Metabolism Processes, Neurodegenerative Disease, Neurology Process, Neuroscience, Oncoproteins, Oncoproteins/Suppressors, Pathways And Processes, Protein Phosphorylation, Ser / Thr Kinases, Signal Transduction

synonyms :

Bcl-2-like protein 11;Bcl2-L-11;Bcl2-interacting mediator of cell death;BCL2L11;BIM;

gene full name :

Bcl-2-like protein 11

molecular weight :

22171 MW

protein function :

Induces apoptosis and anoikis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than isoform BimEL, isoform BimL and isoform BimS. Isoform Bim-gamma induces apoptosis. Isoform Bim-alpha3 induces apoptosis possibly through a caspase-mediated pathway. Isoform BimAC and isoform BimABC lack the ability to induce apoptosis.

subcellular localization :

Endomembrane system ; Peripheral membrane protein . Associated with intracytoplasmic membranes.

tissue specificity :

Isoform BimEL, isoform BimL and isoform BimS are the predominant isoforms and are ubiquitously expressed with a tissue-specific variation. Isoform Bim-gamma is most abundantly expressed in small intestine and colon, and in lower levels in spleen, prostate, testis, heart, liver and kidney.

last modified :

2/6/19 22:57