Anti-Human Glutathione Reductase DyLight® 488 conjugated GSR Antibody

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-Human Glutathione Reductase DyLight® 488 conjugated GSR Antibody

catalog :

A01479-Dyl488

quantity :

50 ug/vial

clonality :

polyclonal

host :

domestic rabbit

conjugate :

DyLight488

reactivity :

human

application :

flow cytometry

product information

SKU :

A01479-Dyl488

Product Name :

Anti-Human Glutathione Reductase DyLight® 488 conjugated GSR Antibody

Size :

50 ug/vial

Clonality :

Polyclonal

Host :

Rabbit

Conjugate :

DyLight®488

Reactivity :

Human

Application(s) :

Flow Cytometry

Application Details :

Flow Cytometry, 1-3μg/1x10^6 cells

Description :

Boster Bio Anti-Human Glutathione Reductase DyLight® 488 conjugated GSR Antibody catalog # A01479-Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.

Concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

GSR

Uniprot ID :

P00390

Immunogen :

E. coli-derived human Glutathione Reductase recombinant protein (Position: K256-R522).

Form :

Liquid

Contents :

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Cross-reactivity :

No cross reactivity with other proteins.

Storage :

At 2-8?C for one year from date of receipt. Protect from light. Do not freeze.

Gene Full Name :

glutathione-disulfide reductase

Synonyms :

Glutathione reductase, mitochondrial; GR; GRase; GSR; GLUR; GRD1

Protein Function :

Maintains high levels of reduced glutathione in the cytosol.

Subcellular Localization :

Isoform Mitochondrial: Mitochondrion.

Background :

Glutathione reductase (GR), also known as glutathione-disulfide reductase (GSR), is an enzyme that in humans is encoded by the GSR gene. This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.

Research Category :

Cancer, Cell Biology, Metabolism, Mitochondrial, Mitochondrial Markers, Mitochondrial Metabolism, Oxidative Stress, Pathways And Processes, Redox Metabolism, Signal Transduction