Anti-Phospho-Trk B (Y706) NTRK2 Antibody | Boster A01388Y706-1 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-Phospho-Trk B (Y706) NTRK2 Antibody

catalog :

A01388Y706-1

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

polyclonal

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

product information

SKU :

A01388Y706-1

Product Name :

Anti-Phospho-Trk B (Y706) NTRK2 Antibody

Size :

100 ul

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

WB, IHC, IF, ELISA

Application Details :

WB 1:500-1:2000.IHC 1:100-1:300.IF 1:200-1:1000 ELISA 1:20000

Description :

Boster Bio Anti-Phospho-Trk B (Y706) NTRK2 Antibody catalog # A01388Y706-1. Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

1 mg/ml

Gene Name :

NTRK2

Uniprot ID :

Q16620

Immunogen :

Synthesized peptide derived from human Trk B around the phosphorylation site of Y706.

Form :

Liquid

Contents :

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification :

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Isotype :

IgG

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Myeloid differentiation primary response protein MyD88

Synonyms :

Myeloid differentiation primary response protein MyD88; MYD88

Protein Name :

Myeloid differentiation primary response protein MyD88

Molecular Weight :

33233 MW

Protein Function :

Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response (PubMed:15361868, PubMed:18292575). Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed:15361868, PubMed:24316379, PubMed:19506249). Increases IL-8 transcription (PubMed:9013863). Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine (By similarity).

Subcellular Localization :

Cytoplasm

Tissue Specificity :

Ubiquitous.