Anti-Trk B (phospho-Y515) NTRK2 Antibody | Boster A01388Y515 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-Trk B (phospho-Y515) NTRK2 Antibody

catalog :

A01388Y515

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

polyclonal

reactivity :

human

application :

western blot, immunohistochemistry

product information

SKU :

A01388Y515

Product Name :

Anti-Trk B (phospho-Y515) NTRK2 Antibody

Size :

100 ul

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

WB, IHC

Application Details :

WB: 1:500~1:1000 IHC: 1:50~1:200

Description :

Boster Bio Anti-Trk B (phospho-Y515) NTRK2 Antibody catalog # A01388Y515. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Gene Name :

NTRK2

Uniprot ID :

Q16620

Form :

Liquid

Contents :

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification :

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

CD40 ligand

Synonyms :

CD40 ligand; CD40-L; T-cell antigen Gp39; TNF-related activation protein; TRAP; Tumor necrosis factor ligand superfamily member 5; CD154; CD40 ligand, membrane form; CD40 ligand, soluble form; Cd40lg; Cd40l, Tnfsf5;

Protein Name :

CD40 ligand

Molecular Weight :

29370 MW

Protein Function :

Cytokine that binds to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Its cross-linking on T- cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation. Induces the activation of NF- kappa-B and kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4. Involved in immunoglobulin class switching (PubMed:1374165).

Subcellular Localization :

Cell membrane

Tissue Specificity :

Specifically expressed on activated CD4+ T- lymphocytes.