Anti-CDC45L Antibody Picoband™ | Boster A01367-1 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-CDC45L Antibody Picoband™

catalog :

A01367-1

quantity :

100µg/vial

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA

product information

SKU :

A01367-1

Product Name :

Anti-CDC45L Antibody Picoband™

Size :

100µg/vial

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

ELISA, WB

Application Details :

Western blot, 0.1-0.5µg/ml. Direct ELISA, 0.1-0.5µg/ml.

Description :

Boster Bio Anti-CDC45L Antibody Picoband™ catalog # A01367-1. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Gene Name :

CDC45

Uniprot ID :

O75419

Immunogen :

E. coli-derived human CDC45L recombinant protein (Position: E166-A431).

Form :

Lyophilized

Contents :

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na 2 HPO 4 , 0.05mg NaN 3 .

Cross-reactivity :

No cross reactivity with other proteins.

Storage :

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Gene Full Name :

cell division cycle 45

Synonyms :

Cell division control protein 45 homolog; PORC-PI-1; CDC45; CDC45L; CDC45L2; UNQ374/PRO710

Protein Function :

Required for initiation of chromosomal DNA replication.

Subcellular Localization :

Cytoplasm. Nucleus.

Tissue Specificity :

Widely expressed, highest levels are found in adult testis and thymus and in fetal liver.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.

Background :

CDC45 is a protein that in humans is encoded by the CDC45L gene. The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants.

Research Category :

Cell Biology, Cell Cycle, Cell Division, DNA / RNA, DNA Synthesis, Epigenetics and Nuclear Signaling