Anti-Cytokeratin 18 (phospho-S33) KRT18 Antibody | Boster A01357S33 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-Cytokeratin 18 (phospho-S33) KRT18 Antibody

catalog :

A01357S33

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

polyclonal

reactivity :

human

application :

western blot, immunohistochemistry

product information

SKU :

A01357S33

Product Name :

Anti-Cytokeratin 18 (phospho-S33) KRT18 Antibody

Size :

100 ul

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

WB, IHC

Application Details :

WB: 1:500~1:1000 IHC: 1:50~1:200

Description :

Boster Bio Anti-Cytokeratin 18 (phospho-S33) KRT18 Antibody catalog # A01357S33. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Gene Name :

KRT18

Uniprot ID :

P05783

Form :

Liquid

Contents :

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification :

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Integrin alpha-5

Synonyms :

Integrin alpha-5; CD49 antigen-like family member E; Fibronectin receptor subunit alpha; Integrin alpha-F; VLA-5; CD49e; Integrin alpha-5 heavy chain; Integrin alpha-5 light chain; Itga5;

Protein Name :

Integrin alpha-5

Molecular Weight :

115043 MW

Protein Function :

Integrin alpha-5/beta-1 (ITGA5:ITGB1) is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1. ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1. ITGA5:ITGB1 is a receptor for IL1B and binding is essential for IL1B signaling.

Subcellular Localization :

Membrane; Single-pass type I membrane protein. Cell junction, focal adhesion