Anti-Phospho-Vinculin (Y821) VCL Antibody | Boster A01207Y821 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-Phospho-Vinculin (Y821) VCL Antibody

catalog :

A01207Y821

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

immunohistochemistry, immunocytochemistry

product information

SKU :

A01207Y821

Product Name :

Anti-Phospho-Vinculin (Y821) VCL Antibody

Size :

100 ul

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

IHC, IF, ELISA

Application Details :

IHC 1:100-1:300.IF 1:200-1:1000 ELISA 1:20000

Description :

Boster Bio Anti-Phospho-Vinculin (Y821) VCL Antibody catalog # A01207Y821. Tested in ELISA, IF, IHC applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

1 mg/ml

Gene Name :

VCL

Uniprot ID :

P18206

Immunogen :

Synthesized peptide derived from human Vinculin around the phosphorylation site of Y821.

Form :

Liquid

Contents :

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification :

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Isotype :

IgG

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Azurocidin

Synonyms :

Azurocidin

Protein Name :

Azurocidin

Molecular Weight :

26886 MW

Protein Function :

This is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. Binds heparin. The cytotoxic action is limited to many species of Gram- negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. It may play a role in mediating recruitment of monocytes in the second wave of inflammation. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. Acting alone, it does not have antimicrobial activity against the Gram-negative bacteria A.actinomycetemcomitans ATCC 29532, A.actinomycetemcomitans NCTC 9709, A.actinomycetemcomitans FDC-Y4, H.aphrophilus ATCC 13252, E.corrodens ATCC 23834, C.sputigena ATCC 33123, Capnocytophaga sp ATCC 33124, Capnocytophaga sp ATCC 27872 or E.coli ML-35. Has antibacterial activity against C.sputigena ATCC 33123 when acting synergistically with either elastase or cathepsin G.

Subcellular Localization :

Cytoplasmic granule membrane