Anti-Timp2 Antibody | Boster A01037 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-Timp2 Antibody

catalog :

A01037

quantity :

100 ug/200 ul

price :

290 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human, zebrafish

application :

western blot

product information

sku :

A01037

name :

Anti-Timp2 Antibody

price :

290 USD

immunogen :

Synthetic peptide with sequence C-TEKIIHGRQSDH, corresponding to the internal region of the protein sequence.

form :

Liquid

host :

Goat

contents :

Each vial contains the specific antibody at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% BSA.

purification :

Immunogen Affinity Purified

clonality :

Polyclonal

description :

Goat Anti-Timp2 Antibody for timp2 detection tested with WB in Zebrafish.

size :

100 ug/200 ul

reactivity :

zebrafish

applications :

background :

TIMP2 gen is encoded by 5 exons spanning 83 kb of genomic DNA. TIMP2 is 83 kilobase pairs(kb) long with exon-intron splicing sites located in preserved positions among the three members of the TIMP family. The gene for tissue inhibitor of metalloproteinases-2 is localized on human chromosome arm 17q25. TIMP-2 abrogates angiogenic factor-induced endothelial cell proliferation in vitro and angiogenesis in vivo independent of MMP inhibition. The standard product used in this kit is recombinant human TIMP-2 with the molecular mass of 22Kda and 194 amino acid.

gene full name :

Metalloproteinase inhibitor 2

gene name :

TIMP2

protein function :

Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.

research category :

cardiovascular angiogenesis adhesion / ecm matrix metalloproteinases timp signal transduction cytoskeleton / ecm extracellular matrix ecm enzymes mmp inhibitors cancer invasion/microenvironment timps cell biology proteolysis / ubiquitin protease inhibitors metalloprotease inhibitors cardiovascular atherosclerosis thrombosis endothelial mediators/regulators

subcellular localization :

Secreted.

synonyms :

Metalloproteinase inhibitor 2;CSC-21K;Tissue inhibitor of metalloproteinases 2;TIMP-2;TIMP2;

uniprot id :

P16035