Anti-Syndecan-1/SDC1 Antibody Picoband™ | Boster A00991-1 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Syndecan-1/SDC1 Antibody Picoband™

catalog :

A00991-1

quantity :

100 ug/vial

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

product information

SKU :

A00991-1

Product Name :

Anti-Syndecan-1/SDC1 Antibody Picoband™

Size :

100 ug/vial

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human

Application(s) :

Application Details :

Western blot, 0.1-0.5µg/ml, Human.

Application Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-Syndecan-1/SDC1 Antibody Picoband™ catalog # A00991-1. Tested in WB applications. This antibody reacts with Human.

Concentration :

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Gene Name :

SDC1

Uniprot ID :

P18827

Immunogen :

E. coli-derived human Syndecan-1/SDC1 recombinant protein (Position: Q23-G254). Human Syndecan-1/SDC1 shares 69.2% and 69.8% amino acid (aa) sequence identity with mouse and rat Syndecan-1/SDC1, respectively.

Form :

Lyophilized

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Cross-reactivity :

No cross reactivity with other proteins.

Storage :

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Gene Full Name :

Syndecan-1

Synonyms :

Syndecan-1; SYND1; CD138; SDC1; SDC;

Molecular Weight :

32462 MW

Protein Function :

Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix.

Subcellular Localization :

Membrane; Single-pass type I membrane protein. Secreted. Shedding of the ectodomain produces a soluble form.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.

Background :

Syndecan 1 is a protein which in humans is encoded by the SDC1 gene. The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.

Research Category :

Cancer, Cancer Metabolism, Cell Adhesion Proteins, Cell Type Marker, Cytoskeleton / Ecm, Ecm Proteins, Extracellular Matrix, Hematopoietic Progenitors, Invasion/Microenvironment, Lipid And Lipoprotein Metabolism, Lipid Metabolism, Lymphoid, Membrane Proteins, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Metabolism Of Lipids And Lipoproteins, Neurogenesis, Neurology Process, Neuron Marker, Neuroscience, Pathways And Processes, Signal Transduction, Stem Cells, Synapse Marker