Anti-4E-BP1(Ab-45) Antibody | Boster A00968 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-4E-BP1(Ab-45) Antibody

catalog :

A00968

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry

product information

sku :

A00968

status :

Enabled

name :

Anti-4E-BP1(Ab-45) Antibody

category name :

Primary Antibodies, Polyclonal Antibodies, IHC ICC IF Antibodies

gene name :

EIF4EBP1

price various sizes :

5ul sample size / $40 100ul / $299 100ul+Free HRP Secondary BA1054 / $299 100ul+Free Biotin Secondary BA1003 / $299

clonality :

Polyclonal

concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

conjugate :

contents :

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

description :

Polyclonal antibody for 4EBP1/EIF4EBP1 detection. Host: Rabbit.Size: 100ul. Tested applications: IF. Reactive species: Human. 4EBP1/EIF4EBP1 information: Molecular Weight: 12580 MW; .

short description :

Rabbit Polyclonal Antibody for 4E-BP1(Ab-45) (EIF4EBP1) detection. Tested with WB, IHC, IF in Human, Mouse, Rat.

size :

100 ul

sample size available :

5ul, free with shipping charge

uniprot id :

Q13541

host :

Rabbit

immunogen :

Peptide sequence around aa.43~47 (S-T-T-P-G) derived from Human 4E-BP1.

form :

Liquid

purification :

Immunogen affinity purified

storage :

Store at -20 C for one year, at 4 C for one month. We suggest the antibody be aliquotted into small vials and stored frozen at -20 C upon receiving. Avoid repeated freezing and thawing.

application details :

WB, 1:500-1:1000. IHC, 1:50-1:100. Immunofluorescence, 1:100-1:200.

applications :

IF, IHC, WB

reactivity :

Human, Mouse, Rat

image labels :

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using 4E-BP1(Ab-45) antibody A00968(left) or the same antibody preincubated with blocking peptide(right). Western blot analysis of extracts from 293 and HepG2 cells using 4E-BP1(Ab-45) antibody A00968. Immunofluorescence staining of methanol-fixed Hela cells using 4E-BP1(Ab-45) antibody A00968.

competitor equivalent skus :

sc 98602 sc 6936 sc 9977 sc 6025 sc 6024 sc 81149 sc 514073

research category :

Diabetes, Dna / Rna, Epigenetics And Nuclear Signaling, Metabolism, Obesity, Rna Processing, Translation

synonyms :

Eukaryotic translation initiation factor 4E-binding protein 1;4E-BP1;eIF4E-binding protein 1;Phosphorylated heat- and acid-stable protein regulated by insulin 1;PHAS-I;EIF4EBP1;

gene full name :

Eukaryotic translation initiation factor 4E-binding protein 1

molecular weight :

12580 MW

protein function :

Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.

last modified :

2/6/19 22:57