Anti-IL-8 CXCL8 Antibody | Boster A00423 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-IL-8 CXCL8 Antibody

catalog :

A00423

quantity :

1 mL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

polyclonal

reactivity :

human

application :

western blot, immunoprecipitation

product information

SKU :

A00423

Product Name :

Anti-IL-8 CXCL8 Antibody

Size :

1 mL

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human

Application(s) :

WB, IP

Application Details :

Western Blot, 1:500 - 1:2, 000, human

Description :

Boster Bio Anti-IL-8 CXCL8 Antibody catalog # A00423. Tested in IP, WB applications. This antibody reacts with Human.

Concentration :

75 mg/mL by Refractometry

Gene Name :

CXCL8

Uniprot ID :

P10145

Form :

Liquid

Gene Full Name :

Interleukin-8

Synonyms :

Interleukin-8; IL-8; C-X-C motif chemokine 8; Chemokine (C-X-C motif) ligand 8; Emoctakin; Granulocyte chemotactic protein 1; GCP-1; Monocyte-derived neutrophil chemotactic factor; MDNCF; Monocyte-derived neutrophil-activating peptide; MONAP; Neutrophil-activating protein 1; NAP-1; Protein 3-10C; T-cell chemotactic factor; MDNCF-a; GCP/IL-8 protein IV; IL8/NAP1 form I; Interleukin-8; (Ala-IL-8)77; GCP/IL-8 protein II; IL-8 (1-77); IL8/NAP1 form II; MDNCF-b; IL-8 (5-77); IL-8 (6-77); (Ser-IL-8)72; GCP/IL-8 protein I; IL8/NAP1 form III; Lymphocyte-derived neutrophil-activating factor; LYNAP; MDNCF-c; Neutrophil-activating factor; NAF; IL-8 (7-77); GCP/IL-8 protein V; IL8/NAP1 form IV; IL-8 (8-77); GCP/IL-8 protein VI; IL8/NAP1 form V; IL-8 (9-77); GCP/IL-8 protein III; IL8/NAP1 form VI; CXCL8; IL8;

Molecular Weight :

11098 MW

Protein Function :

IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8 (6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8 (5-77) has increased activity on neutrophil activation and IL-8 (7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8 (1-77), respectively.

Subcellular Localization :

Secreted.

Background :

Interleukin-8, also called neutrophil-activating peptide-1 or SCYB8, is a tissue-derived peptide secreted by several types of cells in response to inflammatory stimuli. Monocyte-derived neutrophil chemotactic factor (MDNCF/IL-8, suggested gene symbol IL8) is a cytokine that chemoattracts and activates neutrophils. IL-8 is produced and released from human adipose tissue and from isolated adipocytes in vitro, which may indicate that IL-8 from adipose tissue could be involved in some of the obesity-related complications. The MDNCF/IL-8 gene is placed on the human gene map at position 4q12-q21. This is the same location where at least three other members (platelet factor 4, melanoma growth stimulatory activity, and interferon-gamma induced factor) of the platelet factor 4 gene superfamily reside. Human IL-8 consists of 99 amino acids in precursor form and 79 amino acids in mature form.

Research Category :

Angiogenesis, Cancer, Cardiovascular, Cytokines, Immunology, Innate Immunity, Interleukins, Invasion/Microenvironment