Anti-CD4 Antibody | Boster A00344 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-CD4 Antibody

catalog :

A00344

quantity :

100 ul

price :

279.5 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section

product information

sku :

A00344

name :

Anti-CD4 Antibody

price :

279.5 USD

immunogen :

KLH conjugated synthetic peptide derived from rat CD4 420-457 amino acid.

form :

Liquid

host :

Rabbit

contents :

Buffered solution contains 1% BSA, 50% glycerol and 0.09% sodium azide.

purification :

Protein A Purified.

clonality :

Polyclonal

description :

Rabbit IgG polyclonal antibody for T-cell surface glycoprotein CD4 (CD4) detection. Tested with WB, IHC-P, IF in Human, Mouse, Rat.

size :

100 ul

reactivity :

Human; Mouse; Rat

applications :

IF; IHC-P; WB

gene full name :

T-cell surface glycoprotein CD4

gene name :

CD4

protein function :

Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.

research category :

immunology adaptive immunity t cells stem cells hematopoietic progenitors lymphoid t lymphocytic lineage myeloid dendritic cell lineage monocytic lineage immunology regulatory t cells immune system diseases antiviral signaling hiv-related

storage :

At -20 for one year. After reconstitution, at 4 for one month. It can also be aliquotted and stored frozen at -20 for a longer time.Avoid repeated freezing and thawing.

subcellular localization :

Cell membrane ; Single-pass type I membrane protein . Localizes to lipid rafts. Removed from plasma membrane by HIV-1 Nef protein that increases clathrin-dependent endocytosis of this antigen to target it to lysosomal degradation. Cell surface expression is also down-modulated by HIV-1 Envelope polyprotein gp160 that interacts with, and sequesters CD4 in the endoplasmic reticulum.

synonyms :

T-cell surface glycoprotein CD4;T-cell surface antigen T4/Leu-3;CD4;CD4;

uniprot id :

P01730