Anti-Insulin-like growth factor II IGF2 Antibody | Boster A00335-1 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-Insulin-like growth factor II IGF2 Antibody

catalog :

A00335-1

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA

product information

SKU :

A00335-1

Product Name :

Anti-Insulin-like growth factor II IGF2 Antibody

Size :

100 ul

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

WB, ELISA

Application Details :

WB 1:500-2000 ELISA 1:5000-20000

Description :

Boster Bio Anti-Insulin-like growth factor II IGF2 Antibody catalog # A00335-1. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

1 mg/ml

Gene Name :

IGF2

Uniprot ID :

P01344

Form :

Liquid

Contents :

Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide.

Purification :

IGF2 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Isotype :

IgG

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Dickkopf-related protein 1

Synonyms :

Dickkopf-related protein 1; Dickkopf-1; Dkk-1; hDkk-1; SK; DKK1; UNQ492/PRO1008;

Protein Name :

Dickkopf-related protein 1

Molecular Weight :

28672 MW

Protein Function :

Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6 (PubMed:22000856). DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (PubMed:17143291). Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti- apoptotic activity (By similarity).

Subcellular Localization :

Secreted.

Tissue Specificity :

Placenta