Anti-Caspase-3 CASP3 Antibody | Boster A00334 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Caspase-3 CASP3 Antibody

catalog :

A00334

quantity :

0.1 mg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

polyclonal

reactivity :

human

application :

immunohistochemistry

product information

SKU :

A00334

Product Name :

Anti-Caspase-3 CASP3 Antibody

Size :

0.1 mg

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human

Application(s) :

ELISA, IHC

Application Details :

Caspase-3 antibody can be used for detection of Caspase-3 by immunohistochemistry at 5 µg/mL. Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.

Application Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-Caspase-3 CASP3 Antibody catalog # A00334. Tested in ELISA, IHC applications. This antibody reacts with Human.

Concentration :

1 mg/mL

Gene Name :

CASP3

Uniprot ID :

P42574

Immunogen :

Caspase-3 antibody was raised against a 17 amino acid synthetic peptide near the center of human Caspase-3. The immunogen is located within amino acids 70 - 120 of Caspase-3.

Form :

Liquid

Contents :

Caspase-3 Antibody is supplied in PBS containing 0.02% sodium azide.

Purification :

Caspase-3 Antibody is affinity chromatography purified via peptide column.

Isotype :

IgG

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

succinate dehydrogenase complex flavoprotein subunit A

Synonyms :

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein subunit of complex II; Fp; SDHA; SDH2; SDHF

Protein Function :

Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Can act as a tumor suppressor.

Subcellular Localization :

Mitochondrion inner membrane. Peripheral membrane protein. Matrix side.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for ICC.

Background :

Succinate dehydrogenase complex, subunit A, flavoprotein variant is a protein that in humans is encoded by the SDHA gene. It is mapped to 5p15.33. This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.