Anti-EpCAM Antibody | Boster A00276 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-EpCAM Antibody

catalog :

A00276

quantity :

100 ul

price :

269 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section

product information

sku :

A00276

name :

Anti-EpCAM Antibody

price :

269 USD

immunogen :

KLH conjugated synthetic peptide derived from mouse EpCAM 60-110 amino acid.

form :

Liquid

host :

Rabbit

contents :

Buffered solution contains 1% BSA, 50% glycerol and 0.09% sodium azide.

purification :

Protein A Purified.

clonality :

Polyclonal

description :

Rabbit IgG polyclonal antibody for Epithelial cell adhesion molecule (EPCAM) detection. Tested with WB, IHC-P, IF in Human, Mouse, Rat.

size :

100 ul

reactivity :

Human; Mouse; Rat

applications :

IF; IHC-P; WB

gene full name :

Epithelial cell adhesion molecule

gene name :

EPCAM

protein function :

May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.

research category :

tags & cell markers cell type markers tumor associated tags & cell markers epi / endo-thelial

storage :

At -20 for one year. After reconstitution, at 4 for one month. It can also be aliquotted and stored frozen at -20 for a longer time.Avoid repeated freezing and thawing.

subcellular localization :

Lateral cell membrane ; Single-pass type I membrane protein . Cell junction, tight junction . Colocalizes with CLDN7 at the lateral cell membrane and tight junction.

synonyms :

Epithelial cell adhesion molecule;Ep-CAM;Adenocarcinoma-associated antigen;Cell surface glycoprotein Trop-1;Epithelial cell surface antigen;Epithelial glycoprotein;EGP;Epithelial glycoprotein 314;EGP314;hEGP314;KS 1/4 antigen;KSA;Major gastrointestinal tumor-associated protein GA733-2;Tumor-associated calcium signal transducer 1;CD326;EPCAM;GA733-2, M1S2, M4S1, MIC18, TACSTD1, TROP1;

tissue specificity :

Highly and selectively expressed by undifferentiated rather than differentiated embryonic stem cells (ESC). Levels rapidly diminish as soon as ESC's differentiate (at protein levels). Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinoma.

uniprot id :

P16422