Anti-Phospho-IL-2 alpha (S268) IL2RA Antibody | Boster A00214S268 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Phospho-IL-2 alpha (S268) IL2RA Antibody

catalog :

A00214S268

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

product information

SKU :

A00214S268

Product Name :

Anti-Phospho-IL-2 alpha (S268) IL2RA Antibody

Size :

100 ul

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human

Application(s) :

WB, IHC, IF, ELISA

Application Details :

WB 1:500-1:2000.IHC 1:100-1:300.IF 1:200-1:1000 ELISA 1:10000

Description :

Boster Bio Anti-Phospho-IL-2 alpha (S268) IL2RA Antibody catalog # A00214S268. Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Human.

Concentration :

1 mg/ml

Gene Name :

IL2RA

Uniprot ID :

P01589

Immunogen :

Synthesized peptide derived from human IL-2Ralpha around the phosphorylation site of S268.

Form :

Liquid

Contents :

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification :

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Isotype :

IgG

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Vascular endothelial growth factor A

Synonyms :

Vascular endothelial growth factor A; VEGF-A; Vascular permeability factor; VPF; VEGFA; VEGF;

Protein Name :

Vascular endothelial growth factor A

Molecular Weight :

27042 MW

Protein Function :

Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By similarity).

Subcellular Localization :

Secreted

Tissue Specificity :

Isoform VEGF189, isoform VEGF165 and isoform VEGF121 are widely expressed. Isoform VEGF206 and isoform VEGF145 are not widely expressed. A higher level expression seen in pituitary tumors as compared to the pituitary gland.