Anti-TLR9 Antibody | Boster A00198 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-TLR9 Antibody

catalog :

A00198

quantity :

100 ul

price :

279.5 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

immunocytochemistry, immunohistochemistry - paraffin section

product information

sku :

A00198

name :

Anti-TLR9 Antibody

price :

279.5 USD

immunogen :

KLH conjugated synthetic peptide derived from human TLR9 950-1000 amino acid.

form :

Liquid

host :

Rabbit

contents :

Buffered solution contains 1% BSA, 50% glycerol and 0.09% sodium azide.

purification :

Protein A Purified.

clonality :

Polyclonal

description :

Rabbit IgG polyclonal antibody for Toll-like receptor 9 (TLR9) detection. Tested with IHC-P, IF in Human, Mouse, Rat.

size :

100 ul

reactivity :

Human; Mouse; Rat

applications :

IF; IHC-P

gene full name :

Toll-like receptor 9

gene name :

TLR9

protein function :

Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Controls lymphocyte response to Helicobacter infection.

research category :

immunology innate immunity macrophage / inflamm. immunology immunoglobulins receptors signal transduction adapters transmembrane tlr signaling

storage :

At -20 for one year. After reconstitution, at 4 for one month. It can also be aliquotted and stored frozen at -20 for a longer time.Avoid repeated freezing and thawing.

subcellular localization :

Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Endosome . Lysosome . Cytoplasmic vesicle, phagosome . Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist.

synonyms :

Toll-like receptor 9;CD289;TLR9;UNQ5798/PRO19605;

tissue specificity :

Highly expressed in spleen, lymph node, tonsil and peripheral blood leukocytes, especially in plasmacytoid pre- dendritic cells. Levels are much lower in monocytes and CD11c+ immature dendritic cells. Also detected in lung and liver.

uniprot id :

D1CS56