Anti-NOD2 (Card15) Antibody | Boster A00087 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-NOD2 (Card15) Antibody

catalog :

A00087

quantity :

50 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunoprecipitation

product information

sku :

A00087

status :

Enabled

name :

Anti-NOD2 (Card15) Antibody

category name :

Primary Antibodies, Polyclonal Antibodies, IHC ICC IF Antibodies

gene name :

NOD2

price various sizes :

50 ul / $299 50 ul+Free HRP Secondary BA1054 / $299 50 ul+Free Biotin Secondary BA1003 / $299

clonality :

Polyclonal

concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

conjugate :

contents :

50 ul sera

description :

Polyclonal antibody for NOD2 detection. Host: Rabbit.Size: 100 ug. Tested applications: IP. Reactive species: Human. NOD2 information: Molecular Weight: 115283 MW; Subcellular Localization: Cytoplasm . Membrane . Basolateral cell membrane ; Tissue Specificity: Monocytes-specific.

short description :

Rabbit IgG Polyclonal antibody for NOD2 detection. Tested with WB, IHC, IP in Human.

size :

50 ul

sample size available :

No sample size available

uniprot id :

Q9HC29

host :

Rabbit

immunogen :

A synthetic peptide of human NOD2/CARD15 (amino acids 582-600 LGFLVRAKGVVPGSTAPLE)

form :

Liquid

storage :

Store the antibody at 4 C, stable for 6 months. For long-term storage, store at -20 C. Avoid repeated freeze and thaw cycles.

application details :

WB, 1:1000-1:2000. IHC (paraffin), 1:1000-1:5000. IHC (frozen), Users should optimize. IP, 1:50-1:200.

applications :

IP, IHC, WB

reactivity :

Human

image labels :

Formalin-fixed, paraffin-embedded normal human colon stained for NOD2 expression using primary antibody dilution ratio of 1:2000. A, tissue core from a colon tissue microarray. A1, high magnification of A. Hematoxylin-eosin counterstain. Western blot analysis of NOD2 using primary antibody dilution ratio of 1:2000. 30 ug total protein was loaded per lane. Samples from human tumor cell lines: PPC-1 (prostate carcinoma), NCI-H226 and NCI-H332M (lung carcinoma), SF-268 (glioblastoma), UO-31 and A498 (renal/kidney carcinoma), SK-MEL-5 and SK-MEL-28 (melanoma), and MCF-7 (breast carcinoma). Lymphoma is from a cell line generated from a tumor growing in nude mice following injection of primary human lymphoma cells.

competitor equivalent skus :

sc 23587 sc 30199 sc 56168

research category :

Apoptosis, Caspases Etc, Cell Biology, Intracellular

synonyms :

Nucleotide-binding oligomerization domain-containing protein 2;Caspase recruitment domain-containing protein 15;Inflammatory bowel disease protein 1;NOD2;CARD15, IBD1;

gene full name :

Nucleotide-binding oligomerization domain-containing protein 2

molecular weight :

115283 MW

protein function :

Involved in gastrointestinal immunity. Upon stimulation by muramyl dipeptide (MDP), a fragment of bacterial peptidoglycan, binds the proximal adapter receptor-interacting RIPK2, which recruits ubiquitin ligases as XIAP, BIRC2, BIRC3 and the LUBAC complex, triggering activation of MAP kinases and activation of NF-kappa-B signaling. This in turn leads to the transcriptional activation of hundreds of genes involved in immune response. Required for MDP-induced NLRP1-dependent CASP1 activation and IL1B release in macrophages (PubMed:18511561).

subcellular localization :

Cytoplasm . Membrane . Basolateral cell membrane .

tissue specificity :

Monocytes-specific.

protein name :

Nucleotide-binding oligomerization domain-containing protein 2

last modified :

2/6/19 22:57