Anti-Phospho-c-Myc (T358) Antibody | Boster A00026T358 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-Phospho-c-Myc (T358) Antibody

catalog :

A00026T358

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

immunohistochemistry, immunoprecipitation

product information

SKU :

A00026T358

Product Name :

Anti-Phospho-c-Myc (T358) Antibody

Size :

100 ul

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

IHC, IP, ELISA

Application Details :

IHC 1:100-1:300.IP 1:200-500 ELISA 1:20000

Description :

Boster Bio Anti-Phospho-c-Myc (T358) Antibody catalog # A00026T358. Tested in ELISA, IP, IHC applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

1 mg/ml

Gene Name :

MYC

Uniprot ID :

P01106

Immunogen :

Synthesized peptide derived from human c-Myc around the phosphorylation site of T358.

Form :

Liquid

Contents :

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification :

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Isotype :

IgG

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Endothelial PAS domain-containing protein 1

Synonyms :

Endothelial PAS domain-containing protein 1; EPAS-1; Basic-helix-loop-helix-PAS protein MOP2; Class E basic helix-loop-helix protein 73; bHLHe73; HIF-1-alpha-like factor; HLF; Hypoxia-inducible factor 2-alpha; HIF-2-alpha; HIF2-alpha; Member of PAS protein 2; PAS domain-containing protein 2; EPAS1; BHLHE73, HIF2A, MOP2, PASD2;

Protein Name :

Endothelial PAS domain-containing protein 1

Molecular Weight :

96459 MW

Protein Function :

Transcription factor involved in the induction of oxygen regulated genes. Heterodimerizes with ARNT; heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters (By similarity). Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation requires recruitment of transcriptional coactivators such as CREBBP and probably EP300. Interaction with redox regulatory protein APEX seems to activate CTAD (By similarity).

Subcellular Localization :

Nucleus

Tissue Specificity :

Expressed in most tissues, with highest levels in placenta, lung and heart. Selectively expressed in endothelial cells.