Anti-Phospho-EGFR (Y1110) Antibody | Boster A00023Y1110 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-Phospho-EGFR (Y1110) Antibody

catalog :

A00023Y1110

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

polyclonal

reactivity :

human

application :

western blot, ELISA

product information

SKU :

A00023Y1110

Product Name :

Anti-Phospho-EGFR (Y1110) Antibody

Size :

100 ul

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

WB, ELISA

Application Details :

WB 1:500-1:2000 ELISA 1:20000

Description :

Boster Bio Anti-Phospho-EGFR (Y1110) Antibody catalog # A00023Y1110. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

1 mg/ml

Gene Name :

EGFR

Uniprot ID :

P00533

Immunogen :

Synthesized peptide derived from human EGFR around the phosphorylation site of Y1110.

Form :

Liquid

Contents :

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification :

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Isotype :

IgG

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Integrin alpha-5

Synonyms :

Integrin alpha-5; CD49 antigen-like family member E; Fibronectin receptor subunit alpha; Integrin alpha-F; VLA-5; CD49e; Integrin alpha-5 heavy chain; Integrin alpha-5 light chain; ITGA5; FNRA;

Protein Name :

Integrin alpha-5

Molecular Weight :

114536 MW

Protein Function :

Integrin alpha-5/beta-1 (ITGA5:ITGB1) is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:18635536, PubMed:25398877). ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (PubMed:12807887, PubMed:17158881). ITGA5:ITGB1 is a receptor for IL1B and binding is essential for IL1B signaling (PubMed:29030430).

Subcellular Localization :

Membrane; Single-pass type I membrane protein. Cell junction, focal adhesion