Anti-EGFR (Phospho-Y1092) Antibody | Boster A00023Y1092 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-EGFR (Phospho-Y1092) Antibody

catalog :

A00023Y1092

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

polyclonal

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry

product information

SKU :

A00023Y1092

Product Name :

Anti-EGFR (Phospho-Y1092) Antibody

Size :

100 ul

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human, Mouse

Application(s) :

WB, ICC, IF, IHC

Application Details :

WB:1:1,000-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200

Description :

Boster Bio Anti-EGFR (Phospho-Y1092) Antibody catalog # A00023Y1092. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse.

Gene Name :

EGFR

Uniprot ID :

P00533

Form :

Liquid

Contents :

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification :

ProA affinity purified

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

NLR family CARD domain-containing protein 4

Synonyms :

NLR family CARD domain-containing protein 4; CARD, LRR, and NACHT-containing protein; Clan protein; Caspase recruitment domain-containing protein 12; Ice protease-activating factor; Ipaf; NLRC4; CARD12, CLAN, CLAN1, IPAF; UNQ6189/PRO20215;

Protein Name :

NLR family CARD domain-containing protein 4

Molecular Weight :

116159 MW

Protein Function :

Key component of inflammasomes that indirectly senses specific proteins from pathogenic bacteria and fungi and responds by assembling an inflammasome complex that promotes caspase-1 activation, cytokine production and macrophage pyroptosis (PubMed:15107016). The NLRC4 inflammasome is activated as part of the innate immune response to a range of intracellular bacteria (By similarity).

Subcellular Localization :

Cytoplasm

Tissue Specificity :

Isoform 2 is expressed ubiquitously, although highly expressed in lung and spleen. Isoform 1 is highly expressed in lung, followed by leukocytes especially monocytes, lymph node, colon, brain, prostate, placenta, spleen, bone marrow and fetal liver. Isoform 4 is only detected in brain.