Anti-Phospho-EGFR (S1026) Antibody | Boster A00023S1026 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-Phospho-EGFR (S1026) Antibody

catalog :

A00023S1026

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA

product information

SKU :

A00023S1026

Product Name :

Anti-Phospho-EGFR (S1026) Antibody

Size :

100 ul

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

WB, ELISA

Application Details :

WB 1:500-1:2000 ELISA 1:10000

Description :

Boster Bio Anti-Phospho-EGFR (S1026) Antibody catalog # A00023S1026. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

1 mg/ml

Gene Name :

EGFR

Uniprot ID :

P00533

Immunogen :

Synthesized peptide derived from human EGFR around the phosphorylation site of S1026.

Form :

Liquid

Contents :

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification :

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Isotype :

IgG

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Runt-related transcription factor 2

Synonyms :

Runt-related transcription factor 2; Acute myeloid leukemia 3 protein; Core-binding factor subunit alpha-1; CBF-alpha-1; Oncogene AML-3; Osteoblast-specific transcription factor 2; OSF-2; Polyomavirus enhancer-binding protein 2 alpha A subunit; PEA2-alpha A; PEBP2-alpha A; SL3-3 enhancer factor 1 alpha A subunit; SL3/AKV core-binding factor alpha A subunit; RUNX2; AML3, CBFA1, OSF2, PEBP2A;

Protein Name :

Runt-related transcription factor 2

Molecular Weight :

56648 MW

Protein Function :

Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis (PubMed:28505335, PubMed:28738062, PubMed:28703881). Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1 (I) collagen, LCK, IL-3 and GM-CSF promoters. In osteoblasts, supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE) (By similarity). Inhibits KAT6B-dependent transcriptional activation.

Subcellular Localization :

Nucleus

Tissue Specificity :

Specifically expressed in osteoblasts.