Anti-TGF beta 1/TGFB1 Antibody Picoband™ | Boster A00019-2 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-TGF beta 1/TGFB1 Antibody Picoband™

catalog :

A00019-2

quantity :

100 µg/vial

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

polyclonal

reactivity :

human

application :

immunohistochemistry - paraffin section

product information

SKU :

A00019-2

Product Name :

Anti-TGF beta 1/TGFB1 Antibody Picoband™

Size :

100 µg/vial

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Rat

Application(s) :

IHC-P

Application Details :

Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Rat.

Application Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-TGF beta 1/TGFB1 Antibody Picoband™ catalog # A00019-2. Tested in IHC-P applications. This antibody reacts with Rat.

Concentration :

Adding 0.2 ml of distilled water will yield a concentration of 500 µg/ml.

Gene Name :

TGFB1

Uniprot ID :

P01137

Immunogen :

A synthetic peptide corresponding to a sequence of human TGF beta 1/TGFB1 (HANFCLGPCPYIWSLDTQYSK).

Form :

Lyophilized

Contents :

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification :

Immunogen affinity purified.

Storage :

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Reconstitution :

Adding 0.2 ml of distilled water will yield a concentration of 500 µg/ml.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.

Background :

Prostaglandin-I synthase (EC 5.3.99.4) also known as prostaglandin I2 (prostacyclin) synthase (PTGIS) or CYP8A1 is an enzyme involved in prostanoid biosynthesis that in humans is encoded by the PTGIS gene. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis.