Anti-Stat3 (phospho-Y705) Antibody | Boster A00007Y705-1 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Stat3 (phospho-Y705) Antibody

catalog :

A00007Y705-1

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunoprecipitation

product information

SKU :

A00007Y705-1

Product Name :

Anti-Stat3 (phospho-Y705) Antibody

Size :

100 ul

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

WB, IHC, IP

Application Details :

WB: 1:500~1:1000 IHC: 1:50~1:200 IP: 1:50~1:200

Description :

Boster Bio Anti-Stat3 (phospho-Y705) Antibody catalog # A00007Y705-1. Tested in IP, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Gene Name :

STAT3

Uniprot ID :

P40763

Form :

Liquid

Contents :

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification :

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Dipeptidyl peptidase 4

Synonyms :

Dipeptidyl peptidase 4; 3.4.14.5

Protein Name :

Dipeptidyl peptidase 4

Molecular Weight :

87437 MW

Protein Function :

Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF- kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.

Subcellular Localization :

Dipeptidyl peptidase 4 soluble form: Secreted. Detected in the serum and the seminal fluid.