Anti-p53 (phospho-S315) TP53 Antibody | Boster A00001S315 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-p53 (phospho-S315) TP53 Antibody

catalog :

A00001S315

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

immunohistochemistry, immunoprecipitation

product information

SKU :

A00001S315

Product Name :

Anti-p53 (phospho-S315) TP53 Antibody

Size :

100 ul

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

IHC, IP

Application Details :

IHC: 1:50~1:200 IP: 1:50~1:200

Description :

Boster Bio Anti-p53 (phospho-S315) TP53 Antibody catalog # A00001S315. Tested in IP, IHC applications. This antibody reacts with Human, Mouse, Rat.

Gene Name :

TP53

Uniprot ID :

P04637

Form :

Liquid

Contents :

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification :

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Tumor necrosis factor ligand superfamily member 6

Synonyms :

Tumor necrosis factor ligand superfamily member 6; Apoptosis antigen ligand; APTL; CD95 ligand; CD95-L; Fas antigen ligand; Fas ligand; FasL; CD178; Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form; Receptor-binding FasL ectodomain; Soluble Fas ligand; sFasL; ADAM10-processed FasL form; APL; FasL intracellular domain; FasL ICD; SPPL2A-processed FasL form; SPA; FASLG; APT1LG1, CD95L, FASL, TNFSF6;

Protein Name :

Tumor necrosis factor ligand superfamily member 6

Molecular Weight :

31485 MW

Protein Function :

Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells (PubMed:26334989, PubMed:9228058). Involved in cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development (PubMed:9228058, PubMed:7528780, PubMed:9427603). Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses (By similarity). TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance (By similarity). Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis (PubMed:27806260).

Subcellular Localization :

Cell membrane