Anti-Phospho-p53 (S315) TP53 Antibody | Boster A00001S315-1 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-Phospho-p53 (S315) TP53 Antibody

catalog :

A00001S315-1

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

polyclonal

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunoprecipitation

product information

SKU :

A00001S315-1

Product Name :

Anti-Phospho-p53 (S315) TP53 Antibody

Size :

100 ul

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human

Application(s) :

WB, IHC, IP, ELISA

Application Details :

WB 1:500-1:2000.IHC 1:100-1:300.IP 1:200-500 ELISA 1:10000

Description :

Boster Bio Anti-Phospho-p53 (S315) TP53 Antibody catalog # A00001S315-1. Tested in ELISA, IP, IHC, WB applications. This antibody reacts with Human.

Concentration :

1 mg/ml

Gene Name :

TP53

Uniprot ID :

P04637

Immunogen :

Synthesized peptide derived from human p53 around the phosphorylation site of S315.

Form :

Liquid

Contents :

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification :

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Isotype :

IgG

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Midkine

Synonyms :

Midkine; MK; Amphiregulin-associated protein; ARAP; Midgestation and kidney protein; Neurite outgrowth-promoting factor 2; Neurite outgrowth-promoting protein; MDK; MK1, NEGF2;

Protein Name :

Midkine

Molecular Weight :

15585 MW

Protein Function :

Developmentally regulated, secreted growth factor homologous to pleiotrophin (PTN), which has heparin binding activity. Binds anaplastic lymphoma kinase (ALK) which induces ALK activation and subsequent phosphorylation of the insulin receptor substrate (IRS1), followed by the activation of mitogen-activated protein kinase (MAPK) and PI3-kinase, and the induction of cell proliferation. Involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. Also involved in early fetal adrenal gland development (By similarity).

Subcellular Localization :

Secreted.

Tissue Specificity :

Expressed in various tumor cell lines. In insulinoma tissue predominantly expressed in precancerous lesions.