Anti-PTOV1 Antibody | Boster Immunoleader RP1087 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-PTOV1 Antibody

catalog :

RP1087

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, rat

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-PTOV1 Antibody

Catalog Number :

RP1087

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Prostate tumor-overexpressed gene 1 protein(PTOV1) detection. Tested with WB in Human;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: rat Predicted to work with: human

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Rat; Predicted Species: Human

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human PTOV1 (385-414aa NFVNGIRRVIANQQQVLQRNLEQEQQQRGM), different from the related mouse and rat sequences by one amino acid.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Prostate tumor overexpressed gene 1 protein is a protein that in humans is encoded by the PTOV1 gene. It is mapped to 19q13.33. This gene encodes a protein that was found to be overexpressed in prostate adenocarcinomas. The encoded protein was found to interact with the lipid raft protein flotillin-1 and shuttle it from the cytoplasm to the nucleus in a cell cycle dependent manner. Alternative splicing of this gene results in multiple transcript variants.

Reference :

1. "Entrez Gene: PTOV1 prostate tumor overexpressed gene 1". 2. Santamaria A, Castellanos E, Gomez V, Benedit P, Renau-Piqueras J, Morote J, Reventos J, Thomson TM, Paciucci R (Feb 2005). "PTOV1 enables the nuclear translocation and mitogenic activity of flotillin-1, a major protein of lipid rafts". Mol Cell Biol 25 (5): 1900–11. 3. Santamaria A, Fernandez PL, Farre X, Benedit P, Reventos J, Morote J, Paciucci R, Thomson TM (Feb 2003)."PTOV-1, a novel protein overexpressed in prostate cancer, shuttles between the cytoplasm and the nucleus and promotes entry into the S phase of the cell division cycle". Am J Pathol 162 (3): 897–905.

Gene Name :

PTOV1

Protein Name :

Prostate tumor-overexpressed gene 1 protein

Gene Full Name :

prostate tumor overexpressed 1

Synonyms :

ACID2 antibody Activator interaction domain containing protein 2 antibody Gcap3 antibody prostate tumor overexpressed 1 antibody Prostate tumor overexpressed gene 1 antibody PTOV 1 antibody

Uniprot ID :

Q86YD1

more info or order :

Boster Immunoleader product webpage