Anti-Endomucin Antibody | Boster Immunoleader RP1084 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-Endomucin Antibody

catalog :

RP1084

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-Endomucin Antibody

Catalog Number :

RP1084

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Endomucin(EMCN) detection. Tested with WB in Human;Mouse.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, mouse

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Mouse

Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human Endomucin (225-258aa ENGNDQPQSDKESVKLLTVKTISHESGEHSAQGK), identical to the related mouse sequence, and different from the related rat sequence by one amino acid.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Endomucin is a protein that in humans is encoded by the EMCN gene. It is mapped to 4q24. EMCN is a mucin-like sialoglycoprotein that interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix. Using suppression subtractive hybridization (SSH), people found endomucin a potential cell surface marker upregulated. Human endomucin is predicted to encode a 261-aa, 27.5-kDa protein with a transmembrane sequence and multiple glycosylation sites. Northern and in situ hybridization studies show that human endomucin expression is largely, if not uniquely, endothelial cell-specific. And human endomucin is present abundantly in highly vascular tissues such as heart, kidney, and lung.

Reference :

1. "Entrez Gene: EMCN endomucin". 2. Kinoshita M, Nakamura T, Ihara M, Haraguchi T, Hiraoka Y, Tashiro K, Noda M (Jun 2001). "Identification of human endomucin-1 and -2 as membrane-bound O-sialoglycoproteins with anti-adhesive activity". FEBS Lett 499(1-2): 121–6. 3. Liu C, Shao ZM, Zhang L, Beatty P, Sartippour M, Lane T, Livingston E, Nguyen M (Oct 2001). "Human endomucin is an endothelial marker". Biochem Biophys Res Commun 288 (1): 129–36.

Gene Name :

EMCN

Protein Name :

Endomucin

Gene Full Name :

endomucin

Synonyms :

EMCN antibody EMCN2 antibody Endomucin 2 antibody Endomucin antibody Endomucin-2 antibody Endothelial sialomucin antibody Gastric cancer antigen Ga34 antibody MUC-14 antibody MUC14 antibody MUCEN_HUMAN antibody Mucin 14 antibody Mucin-14 antibody

Uniprot ID :

Q9ULC0

more info or order :

Boster Immunoleader product webpage