Anti-CD30 Antibody | Boster Immunoleader RP1029 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-CD30 Antibody

catalog :

RP1029

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot

publications citing this reagent :

Hang C, Shi J, Tian J, Li J, Wu W, Yin H. Effect of systemic LPS injection on cortical NF-kappaB activity and inflammatory response following traumatic brain injury in rats. Brain Res. 2004;1026:23-32 pubmed

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-CD30 Antibody

Catalog Number :

RP1029

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 8(TNFRSF8) detection. Tested with WB in Human.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived human CD30 recombinant protein (Position: T322-K595). Human CD30 shares 60% and 57% amino acid (aa) sequences identity with mouse and rat CD30, respectively.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. This gene is mapped to 1p36.22. CD30 is expressed in embryonal carcinoma but not in seminoma and is thus a useful marker in distinguishing between these germ cell tumors. CD30 mast cell activation represents an IgE-independent activation pathway, which is important for understanding cutaneous inflammation associated with mast cells. In addition to those, CD30 is also associated with anaplastic large cell lymphoma.

Reference :

1. Fischer, M., Harvima, I. T., Carvalho, R. F. S., Moller, C., Naukkarinen, A., Enblad, G., Nilsson, G. Mast cell CD30 ligand is upregulated in cutaneous inflammation and mediates degranulation-independent chemokine secretion. J. Clin. Invest. 116: 2748-2756, 2006. 2. Gorczyca W, Tsang P, Liu Z, et al. (February 2003). "CD30-positive T-cell lymphomas co-expressing CD15: an immunohistochemical analysis". Int. J. Oncol. 22 (2): 319–24. 3. Teng LH, Lu DH, Xu QZ, Fu YJ, Yang H, He ZL (2005). "[Expression and diagnostic significance of OCT4, CD117 and CD30 in germ cell tumors]". Zhonghua Bing Li Xue Za Zhi (in Chinese) 34 (11): 711–5.

Gene Name :

TNFRSF8

Protein Name :

Tumor necrosis factor receptor superfamily member 8

Gene Full Name :

tumor necrosis factor receptor superfamily, member 8

Synonyms :

CD 30 antibody CD153 antibody CD30 antibody CD30 antigen antibody CD30L receptor antibody Cytokine receptor CD30 antibody D1S166E antibody KI 1 antibody Ki 1 antigen antibody Ki-1 antigen antibody KI1 antibody Lymphocyte activation antigen CD30 antibody TNFRSF 8 antibody TNFRSF8 antibody TNR8_HUMAN antibody Tumor Necrosis Factor Receptor Superfamily Member 8 antibody

Uniprot ID :

P28908

more info or order :

Boster Immunoleader product webpage