Anti-IL12 p40 Antibody | Boster Immunoleader RP1028 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-IL12 p40 Antibody

catalog :

RP1028

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

rat

application :

western blot

publications citing this reagent :

Dong L, Xia S, Chen H, Chen J, Zhang J. Anti-arthritis activity of cationic materials. J Cell Mol Med. 2010;14:2015-24 pubmed publisher

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-IL12 p40 Antibody

Catalog Number :

RP1028

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Interleukin-12 subunit beta(IL12B) detection. Tested with WB in Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: rat

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Rat

Notes :

WB: The detection limit for IL12 p40 is approximately 0.25ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived rat IL12 p40 recombinant protein (Position: M23-S321).

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Subunit beta of interleukin 12, also known as interleukin 12B, or IL12B, is a subunit of human interleukin 12. It is mapped to 5q33.3. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease.

Reference :

1. Entrez Gene: IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) 2. Yokouchi, Y., Nukaga, Y., Shibasaki, M., Noguchi, E., Kimura, K., Ito, S., Nishihara, M., Yamakawa-Kobayashi, K., Takeda, K., Imoto, N., Ichikawa, K., Matsui, A., Hamaguchi, H., Arinami, T. Significant evidence for linkage of mite-sensitive childhood asthma to chromosome 5q31-q33 near the interleukin 12 B locus by a genome-wide search in Japanese families. Genomics 66: 152-160, 2000.

Gene Name :

IL12B

Protein Name :

Interleukin-12 subunit beta

Gene Full Name :

interleukin 12B

Synonyms :

40 kD Subunit antibody CLMF 2 antibody CLMF antibody CLMF p40 antibody CLMF2 antibody Cytotoxic lymphocyte maturation factor 2 antibody Cytotoxic lymphocyte maturation factor 2 p40 antibody Cytotoxic lymphocyte maturation factor 40 kDa subunit antibody IL 12 subunit p40 antibody IL 12B antibody IL-12 subunit p40 antibody IL-12B antibody IL12 subunit p40 antibody IL12B antibody IL12B_HUMAN antibody Interleukin 12 beta chain antibody Interleukin 12 p40 antibody Interleukin 12 subunit beta antibody Interleukin 12B antibody Interleukin-12 subunit beta antibody Natural killer cell stimulatory factor 2 antibody natural killer cell stimulatory factor 40 kD subunit antibody NK cell stimulatory factor chain 2 antibody NKSF 2 antibody NKSF antibody NKSF2 antibody p40 antibody TcMF antibody TSF antibody

Uniprot ID :

Q9R278

more info or order :

Boster Immunoleader product webpage