product summary
request information :
company name :
Boster Immunoleader
product type :
antibody
product name :
Anti-human IL7 Antibody
catalog :
RP1013
quantity :
100 ug/vial
price :
240 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human
application :
western blot, ELISA
product information
Product Name :
Anti-human IL7 Antibody
Catalog Number :
RP1013
Clonality :
Polyclonal
Description short :
Rabbit IgG polyclonal antibody for Interleukin-7(IL7) detection. Tested with WB, ELISA in Human.
Price :
240 USD
Ig type :
Rabbit IgG
Size :
100 ug/vial
Form :
Lyophilized
Specificity :
No cross reactivity with other proteins.
Reactivity :
Reacts with: human
Applications :
WB,ELISA
Western blot :
Concentration: 0.1-0.5μg/ml; Species: Human
ELISA :
Concentration: 0.1-0.5μg/ml; Species: Human
Notes :
Other applications have not been tested. Optimal dilutions should be determined by end users.
Immunogen :
E. coli-derived human IL-7 recombinant protein(Position: D26-H177).
Contents :
Each vial contains 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purification :
Immunogen affinity purified.
Reconstitution :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage :
At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Relevant detection systems :
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.
Background :
IL-7, Interleukin 7, is a protein that in humans is encoded by the IL-7 gene. IL-7 a hematopoietic growth factor secreted by stromal cells in the red marrow and thymus. It is also produced by keratinocytes, dendritic cells, hepatocytes, neurons, and epithelial cells but is not produced by lymphocytes. By the combination of approaches, IL-7 is located on 8q12-q13. IL-7 is critical for early T-cell development and homeostasis of naive and memory CD8-positive T cells. It signals through the IL-7 receptor complex, which consists of the IL7R-alpha chain and the common IL2R-gamma chain is critical for early T-cell development and homeostasis of naive and memory CD8 -positive T cells. It signals through the IL-7 receptor complex, which consists of the IL7R-alpha chain and the common IL2R-gamma chain.
Reference :
1. O'Connor, A. M., Crawley, A. M., Angel, J. B.Interleukin-7 enhances memory CD8+ T-cell recall responses in health but its activity is impaired in human immunodeficiency virus infection.Immunology 131: 525-536, 2010. 2. Sutherland, G. R., Baker, E., Fernandez, K. E. W., Callen, D. F., Goodwin, R. G., Lupton, S., Namen, A. E., Shannon, M. F., Vadas, M. A.The gene for human interleukin 7 (IL7) is at 8q12-13.Hum. Genet. 82: 371-372, 1989. 3. Watanabe, M., Ueno, Y., Yajima, T., Iwao, Y., Tsuchiya, M., Ishikawa, H., Aiso, S., Hibi, T., Ishii, H.Interleukin 7 is produced by human intestinal epithelial cells and regulates the proliferation of intestinal mucosal lymphocytes.J. Clin. Invest. 95: 2945-2953, 1995.
Gene Name :
IL7
Protein Name :
Interleukin-7(IL-7)
Gene Full Name :
interleukin 7
Synonyms :
IL 7 antibody IL-7 antibody Il7 antibody Interleukin 7 antibody Interleukin-7 antibody
Uniprot ID :
P13232
company information
Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com
925.485.4527
headquarters: USA
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