Anti-human SCF Antibody | Boster Immunoleader RP1010 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-human SCF Antibody

catalog :

RP1010

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot, ELISA

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-human SCF Antibody

Catalog Number :

RP1010

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Kit ligand/Mast cell growth factor(KITLG) detection. Tested with WB, ELISA in Human.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

WB,ELISA

Western blot :

Concentration: 0.1-0.5μg/ml; Species: Human

ELISA :

Concentration: 0.1-0.5μg/ml; Species: Human

Notes :

Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E. coli-derived human SCF recombinant protein(Position: E26-A190).

Contents :

Each vial contains 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Stem Cell Factor(also known as SCF, kit-ligand, KL, or steel factor) is a cytokine that binds to the c-Kit receptor(CD117). The SCF gene is mapped to 12q21.32. SCF can exist both as a transmembrane protein and a soluble protein. This cytokine plays an important role in hematopoiesis(formation of blood cells), spermatogenesis, and melanogenesis. SCF may be used along with other cytokines to culture HSCs and hematopoietic progenitors. The expansion of these cells ex-vivo(outside the body) would allow advances in bone-marrow transplantation, in which HSCs are transferred to a patient to re-establish blood formation. One of the problems of injecting SCF for therapeutic purposes is that SCF activates mast cells. The injection of SCF has been shown to cause allergic-like symptoms and the proliferation of mast cells and melanocytes.

Reference :

1. Geissler, E. N., Liao, M., Brook, J. D., Martin, F. H., Zsebo, K. M., Housman, D. E., Galli, S. J.Stem cell factor (SCF), a novel hematopoietic growth factor and ligand for c-kit tyrosine kinase receptor, maps on human chromosome 12 between 12q14.3 and 12qter.Somat. Cell Molec. Genet. 17: 207-214, 1991. 2. Heissig, B., Hattori, K., Dias, S., Friedrich, M., Ferris, B., Hackett, N. R., Crystal, R. G., Besmer, P., Lyden, D., Moore, M. A. S., Werb, Z., Rafii, S.Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of Kit-ligand.Cell 109: 625-637, 2002.

Gene Name :

KITLG

Protein Name :

Kit ligand

Gene Full Name :

KIT ligand

Synonyms :

C kit ligand antibody C-kit ligand antibody Ckit ligand antibody DKFZp686F2250 antibody familial progressive hyperpigmentation 2 antibody FPH2 antibody KIT ligand antibody Kitl antibody KITLG antibody KL 1 antibody KL1 antibody Mast cell growth factor antibody MGF antibody SCF antibody SF antibody SHEP7 antibody sKITLG antibody Soluble KIT ligand antibody Steel factor antibody Stem cell factor antibody Stem cell factor precursor antibody

Uniprot ID :

P21583

more info or order :

Boster Immunoleader product webpage