Boster Immunoleader

antibody

Anti-human IL4 Antibody

RP1009

100 ug/vial

240 USD

polyclonal

rabbit

western blot, ELISA, immunoprecipitation, immunohistochemistry - paraffin section

Anti-human IL4 Antibody

RP1009

Polyclonal

Rabbit IgG polyclonal antibody for Interleukin-4(IL4) detection. Tested with WB, IHC-P, ELISA, Neu, IP in Human.

240 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human

WB,IHC-P,ELISA,Neu,IP

Concentration: 0.1-0.5μg/ml; Species: Human

Concentration: 0.5-1μg/ml; Species: Human

Concentration: 0.1-0.5μg/ml; Species: Human

Species: Human

Species: Human

By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

E. coli-derived human IL-4 recombinant protein(Position: H25-S153).

Each vial contains 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

Interleukin-4(IL-4), also knowns as a B-cell stimulatory factor1(BSF1), is an immunomodulatory cytokine, which can inhibit the growth of tumour cells. The human cDNA contains a single open reading frame encoding a protein of 153 amino acids, including a putative signal peptide. IL-4 may act as an autocrine growth factor in pancreatic cancer cells and also give rise to the possibility that cancer-derived IL-4 may suppress cancer-directed immunosurveillance in vivo in addition to its growth-promoting effects, thereby facilitating pancreatic tumor growth and metastasis. The mouse and human genes and their protein products show structural and functional similarities. The human IL-4 gene, which occurs as a single copy in the haploid genome, is mapped on chromosome 5.2 The standard product used in this kit is recombinant human IL-4, consisting of 130 amino acids with the molecular mass of 14KDa.

1. Prokopchuk, O.; Liu, Y.; Henne-Bruns, D.; Kornmann, M. Interleukin-4 enhances proliferation of human pancreatic cancer cells: evidence for autocrine and paracrine actions. Br J Cancer.2005 Mar 14;92(5):921-8. 2. Arai, N.; Nomura, D.; Villaret, D.; DeWaal Malefijt, R.; Seiki, M.; Yoshida, M.; Minoshima, S.; Fukuyama, R.; Maekawa, M.; Kudoh, J.; Shimizu, N.; Yokota, K.; Abe, E.; Yokota, T.; Takebe, Y.; Arai, K. Complete nucleotide sequence of the chromosomal gene for human IL-4 and its expression. J. Immun. 142: 274-282, 1989.

IL4

Interleukin-4(IL-4)

interleukin 4

B cell growth factor 1 antibody B cell IgG differentiation factor antibody B Cell Stimulatory Factor 1 antibody B-cell stimulatory factor 1 antibody BCGF 1 antibody BCGF1 antibody Binetrakin antibody BSF 1 antibody BSF-1 antibody BSF1 antibody HCGF antibody Hodgkin’s Cell Growth Factor antibody IA Inducing Factor antibody IGG1 induction factor antibody IL 4 antibody IL-4 antibody IL4 antibody Il4e12 antibody Interleukin 4 antibody Interleukin 4, isoform 1 antibody Interleukin-4 antibody Interleukin4 antibody Lymphocyte stimulatory factor 1 antibody Macrophage fusion factor antibody Mast cell growth factor 2 antibody MCGF2 antibody MFF antibody MGC79402 antibody Pitrakinra antibody T cell growth factor 2 antibody TCGF2 antibody

P05112