Anti-human FGF1 Antibody | Boster Immunoleader RP1005 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-human FGF1 Antibody

catalog :

RP1005

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot, ELISA, immunoprecipitation, immunohistochemistry - paraffin section

publications citing this reagent :

Zhou Y, Ren L, Zhu J, Yan S, Wang H, Song N, et al. Construction of a recombinant human FGF1 expression vector for mammary gland-specific expression in human breast cancer cells. Mol Cell Biochem. 2011;354:39-46 pubmed publisher

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Boster Immunoleader product webpage

product information

Product Name :

Anti-human FGF1 Antibody

Catalog Number :

RP1005

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Fibroblast growth factor 1(FGF1) detection. Tested with WB, IHC-P, ELISA, Neu, IP in Human.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

WB,IHC-P,ELISA,Neu,IP

Western blot :

Concentration: 0.1-0.5μg/ml; Species: Human

Immunohistochemistry(Paraffin-embedded S ... :

Concentration: 0.5-1μg/ml; Species: Human

ELISA :

Concentration: 0.1-0.5μg/ml; Species: Human

Neutralization :

Species: Human

Immunoprecipitation :

Species: Human

Notes :

By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E. coli-derived human FGF1 recombinant protein(Position: F16-D155).

Contents :

Each vial contains 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

Background :

Fibroblast growth factor 1(acidic), also known as FGF1/ECGF/HBGF1, is a human gene which is mapped to 5q31. Human FGF1 shares 96% amino acid sequence homology with both rat and mouse. The protein encoded by this gene is a member of the fibroblast growth factor(FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is though to be involved in organogenesis. Additionally, Acidic fibroblast growth factor is derived from beta-endothelial cell growth factor(ECGFB) by posttranslational processing. Alpha-ECGF is also derived from ECGFB in the same manner.

Reference :

1. Le Beau, M. M.; Espinosa, R., III; Neuman, W. L.; Stock, W.; Roulston, D.; Larson, R. A.; Keinanen, M.; Westbrook, C. A. : Cytogenetic and molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases. Proc. Nat. Acad. Sci. 90: 5484-5488, 1993. 2. Mergia, A.; Eddy, R.; Abraham, J. A.; Fiddes, J. C.; Shows, T. B. : The genes for basic and acidic fibroblast growth factors are on different human chromosomes. Biochem. Biophys. Res. Commun. 138: 644-651, 1986. 3. Burgess, W. H.; Mehlman, T.; Marshak, D. R.; Fraser, B. A.; Maciag, T. : Structural evidence that endothelial cell growth factor beta is the precursor of both endothelial cell growth factor alpha and acidic fibroblast growth factor. Proc. Nat. Acad. Sci. 83: 7216-7220, 1986.

Gene Name :

FGF1

Protein Name :

Fibroblast growth factor 1

Gene Full Name :

fibroblast growth factor 1(acidic)

Synonyms :

Acidic fibroblast growth factor antibody AFGF antibody Beta endothelial cell growth factor antibody Beta-endothelial cell growth factor antibody ECGF antibody ECGF beta antibody ECGF-beta antibody ECGFA antibody ECGFB antibody Endothelial cell growth factor alpha antibody Endothelial Cell Growth Factor beta antibody FGF 1 antibody FGF alpha antibody Fgf1 antibody FGFA antibody Fibroblast Growth Factor 1 Acidic antibody Fibroblast growth factor 1 antibody GLIO703 antibody HBGF 1 antibody HBGF-1 antibody HBGF1 antibody Heparin binding growth factor 1 antibody Heparin binding growth factor 1 precursor antibody Heparin-binding growth factor 1 antibody

Uniprot ID :

P05230

more info or order :

Boster Immunoleader product webpage