Anti-human BCL-2 Antibody | Boster Immunoleader RP1003 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-human BCL-2 Antibody

catalog :

RP1003

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot, ELISA, immunoprecipitation

publications citing this reagent :

Sun W, Liu J, Huan Y, Zhang C. Intracranial injection of recombinant stromal-derived factor-1 alpha (SDF-1α) attenuates traumatic brain injury in rats. Inflamm Res. 2014;63:287-97 pubmed publisher

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-human BCL-2 Antibody

Catalog Number :

RP1003

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Apoptosis regulator Bcl-2(BCL2) detection. Tested with WB, ELISA, Neu, IP in Human.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

WB,ELISA,Neu,IP

Western blot :

Concentration: 0.1-0.5μg/ml; Species: Human

ELISA :

Concentration: 0.1-0.5μg/ml; Species: Human

Neutralization :

Species: Human

Immunoprecipitation :

Species: Human

Notes :

Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E. coli-derived human BCL-2 recombinant protein(Position: M1-D211).

Contents :

Each vial contains 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Immunoreactive BCL2 protein in the neoplastic cells of almost all follicular lymphomas whereas no BCL2 protein was detected in follicles affected by nonneoplastic processes or in normal lymphoid tissue. Every tumor with molecular-genetic evidence of t(14;18) translocation expressed detectable levels of BCL2 protein, regardless of whether the breakpoint was located in or at a distance from the BCL2 gene. Overexpression of BCL2 blocks the apoptotic death of a pro-B-lymphocyte cell line.

Reference :

1. Ngan, B.-Y.; Chen-Levy, Z.; Weiss, L. M.; Warnke, R. A.; Cleary, M. L. : Expression in non-Hodgkin's lymphoma of the BCL-2 protein associated with the t(14;18) chromosomal translocation. New Eng. J. Med. 318: 1638-1644, 1988. 2. Hockenbery, D.; Nunez, G.; Milliman, C.; Schreiber, R. D.; Korsmeyer, S. J. : Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 348: 334-336, 1990.

Gene Name :

BCL2

Protein Name :

Apoptosis regulator Bcl-2

Gene Full Name :

B-cell CLL/lymphoma 2

Synonyms :

Apoptosis regulator Bcl2 antibody B cell CLL antibody B cell lymphoma 2 antibody B cell lymphoma protein 2 alpha isoform antibody B cell lymphoma protein 2 antibody B-cell CLL/lymphoma 2 antibody B-cell leukemia/lymphoma 2 antibody Bcl 2 antibody bcl2a antibody Leukemia /lymphoma, B-cell, 2 antibody Oncogene B cell leukemia 2 antibody Oncogene B-cell leukemia 2 antibody

Uniprot ID :

P10415

more info or order :

Boster Immunoleader product webpage