Anti-Wnt3 Antibody | Boster Immunoleader PB9619 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-Wnt3 Antibody

catalog :

PB9619

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-Wnt3 Antibody

Catalog Number :

PB9619

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Proto-oncogene Wnt-3(WNT3) detection. Tested with WB in Human.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence in the middle region of human Wnt3 (185-207aa AMNKHNNEAGRTTILDHMHLKCK), identical to the related mouse sequence.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.

Reference :

1. "Entrez Gene: WNT3 wingless-type MMTV integration site family, member 3". 2. Liu P, Wakamiya M, Shea MJ et al. (1999). "Requirement for Wnt3 in vertebrate axis formation".Nat. Genet. 22 (4): 361–5. 3. Roelink H, Wang J, Black DM, Solomon E, Nusse R (Dec 1993). "Molecular cloning and chromosomal localization to 17q21 of the human WNT3 gene". Genomics 17 (3): 790–2.

Gene Name :

WNT3

Protein Name :

Proto-oncogene Wnt-3

Gene Full Name :

wingless-type MMTV integration site family, member 3

Synonyms :

Int 4 antibody INT4 antibody MGC131950 antibody MGC138321 antibody MGC138323 antibody Proto-oncogene Int-4 homolog antibody Proto-oncogene Wnt-3 antibody wingless type MMTV integration site family member 3 antibody Wnt 3 proto oncogene protein antibody WNT 3 proto oncogene protein precursor antibody wnt3 antibody WNT3_HUMAN antibody

Uniprot ID :

P56703

more info or order :

Boster Immunoleader product webpage