Anti-MNAT1 Antibody | Boster Immunoleader PB9614 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-MNAT1 Antibody

catalog :

PB9614

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry - paraffin section

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-MNAT1 Antibody

Catalog Number :

PB9614

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for CDK-activating kinase assembly factor MAT1(MNAT1) detection. Tested with WB, IHC-P in Human;Mouse;Rat.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, mouse, rat

Applications :

WB,IHC-P

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat

Immunohistochemistry(Paraffin-embedded S ... :

Concentration: 0.5-1μg/ml; Tested Species: Human, Mouse, Rat

Notes :

Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived human MNAT1 recombinant protein (Position: L92-A278). Human MNAT1 shares 93% amino acid (aa) sequence identity with mouse MNAT1.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

Background :

CDK-activating kinase assembly factor MAT1 is an enzyme that in humans is encoded by the MNAT1 gene. The protein encoded by this gene, along with cyclin H and CDK7, forms the CDK-activating kinase (CAK) enzymatic complex. This complex activates several cyclin-associated kinases and can also associate with TFIIH to activate transcription by RNA polymerase II. Two transcript variants encoding different isoforms have been found for this gene.

Reference :

1. "Entrez Gene: MNAT1 menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)". 2. Eki T, Okumura K, Abe M, Kagotani K, Taguchi H, Murakami Y, Pan ZQ, Hanaoka F (April 1998). "Mapping of the human genes encoding cyclin H (CCNH) and the CDK-activating kinase (CAK) assembly factor MAT1 (MNAT1) to chromosome bands 5q13.3-q14 and 14q23, respectively". Genomics 47 (1): 115–20. 3. Talukder AH, Mishra SK, Mandal M, Balasenthil S, Mehta S, Sahin AA, Barnes CJ, Kumar R (March 2003). "MTA1 interacts with MAT1, a cyclin-dependent kinase-activating kinase complex ring finger factor, and regulates estrogen receptor transactivation functions". J. Biol. Chem. 278 (13): 11676–85.

Gene Name :

MNAT1

Protein Name :

CDK-activating kinase assembly factor MAT1

Gene Full Name :

MNAT CDK-activating kinase assembly factor 1

Synonyms :

MNAT 1 antibody MNAT 1 antibody CAP35 antibody CDK activating kinase assembly factor MAT1 antibody CDK-activating kinase assembly factor MAT1 antibody CDK7/cyclin H assembly factor antibody CDK7/cyclin-H assembly factor antibody Cyclin G1 interacting protein antibody Cyclin-G1-interacting protein antibody MAT1 antibody MAT1_HUMAN antibody Menage a trois 1 (CAK assembly factor) antibody Menage a trois antibody Menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) antibody MNAT CDK activating kinase assembly factor 1 antibody Mnat1 antibody p35 antibody p36 antibody RING finger protein 66 antibody RING finger protein MAT1 antibody RNF66 antibody TFB3 antibody

Uniprot ID :

P51948

more info or order :

Boster Immunoleader product webpage