Anti-MICB Antibody | Boster Immunoleader PB9613 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-MICB Antibody

catalog :

PB9613

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, rat

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-MICB Antibody

Catalog Number :

PB9613

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for MHC class I polypeptide-related sequence B(MICB) detection. Tested with WB in Human;Rat.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, rat

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat

Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the N-terminus of human MICB (23-48aa AEPHSLRYNLMVLSQDESVQSGFLAE).

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

MHC class I polypeptide-related sequence B is a protein that in humans is encoded by the MICB gene. This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants.

Reference :

1. Bahram S, Bresnahan M, Geraghty DE, Spies T (Aug 1994). "A second lineage of mammalian major histocompatibility complex class I genes". Proc Natl Acad Sci U S A 91 (14): 6259–63. 2. "Entrez Gene: MICB MHC class I polypeptide-related sequence B". 3. Leelayuwat C, Townend DC, Degli-Esposti MA et al. (1994). "A new polymorphic and multicopy MHC gene family related to nonmammalian class I.".Immunogenetics 40 (5): 339–51.

Gene Name :

MICB

Protein Name :

MHC class I polypeptide-related sequence B

Gene Full Name :

MHC class I polypeptide-related sequence B

Synonyms :

MHC class I chain related protein B2 antibody MHC class I mic B antigen antibody MHC class I polypeptide related sequence B antibody MHC class I polypeptide-related sequence B antibody MIC B antibody MIC-B antibody MICB antibody MICB_HUMAN antibody PERB11.2 antibody

Uniprot ID :

Q29980

more info or order :

Boster Immunoleader product webpage