Anti-5HT2B Receptor Antibody | Boster Immunoleader PB9600 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-5HT2B Receptor Antibody

catalog :

PB9600

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, rat

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-5HT2B Receptor Antibody

Catalog Number :

PB9600

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for 5-hydroxytryptamine receptor 2B(HTR2B) detection. Tested with WB in Human;Rat.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, rat

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat

Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human 5HT2B Receptor (446-478aa MRLRSSTIQSSSIILLDTLLLTENEGDKTEEQ V), different from the related mouse sequence by six amino acids, and from the related rat sequence by nine amino acids.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

5HT2B Receptor is known as HTR2B. This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved.

Reference :

1. "Entrez Gene: HTR2B 5-hydroxytryptamine (serotonin) receptor 2B". 2. Doly S, Valjent E, Setola V, Callebert J, Hervé D, Launay JM, Maroteaux L (Mar 2008). "Serotonin 5-HT2B receptors are required for 3,4-methylenedioxymethamphetamine-induced hyperlocomotion and 5-HT release in vivo and in vitro". The Journal of Neuroscience28 (11): 2933–40. 3. Schmuck K, Ullmer C, Engels P, Lübbert H (Mar 1994). "Cloning and functional characterization of the human 5-HT2B serotonin receptor". FEBS Letters 342 (1): 85–90.

Gene Name :

HTR2B

Protein Name :

5-hydroxytryptamine receptor 2B

Gene Full Name :

5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled

Synonyms :

5 HT 2B antibody 5 HT 2B receptor antibody 5 HT(2B) antibody 5 HT2B antibody 5 hydroxytryptamine (serotonin) receptor 2B antibody 5 hydroxytryptamine (serotonin) receptor 2B G protein coupled antibody 5 hydroxytryptamine 2B receptor antibody 5 hydroxytryptamine receptor 2B antibody 5-HT-2B antibody 5-HT2B antibody 5-hydroxytryptamine receptor 2B antibody 5HT(2B) antibody 5HT2B_HUMAN antibody 5HT2F antibody Htr 2b antibody Htr2b antibody NP75 protein antibody SEROTONIN 5HT2B RECEPTOR antibody Serotonin receptor 2B antibody Stomach fundus serotonin receptor antibody

Uniprot ID :

P41595

more info or order :

Boster Immunoleader product webpage