Anti-GABRB3 Antibody | Boster Immunoleader PB9595 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-GABRB3 Antibody

catalog :

PB9595

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-GABRB3 Antibody

Catalog Number :

PB9595

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Gamma-aminobutyric acid receptor subunit beta-3(GABRB3) detection. Tested with WB in Human;Mouse; Rat.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: mouse, rat Predicted to work with: human

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Mouse, Rat; Predicted Species: Human

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human GABRB3 (344-375aa EKTAKAKNDRSKSESNRVDAHGNILLTSLEVH), different from the related mouse and rat sequences by five amino acids.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one the subunits of a multi-subunit chloride channel that serves as the receptor for gamma-aminobutyric acid, a major inhibitory neurotransmitter of the mammalian nervous system. And this gene is located on the long arm of chromosome 15 in a cluster with two other genes encoding related subunits of the family. It may be associated with the pathogenesis of several disorders including Angelman syndrome, Prader-Willi syndrome, nonsyndromic orofacial clefts, epilepsy and autism. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Reference :

1. DeLorey TM, Sahbaie P, Hashemi E, Homanics GE, Clark JD (March 2008)."Gabrb3 gene deficient mice exhibit impaired social and exploratory behaviors, deficits in non-selective attention and hypoplasia of cerebellar vermal lobules: a potential model of autism spectrum disorder". Behav. Brain Res. 187 (2): 207–20. 2. "Entrez Gene: GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3".

Gene Name :

GABRB3

Protein Name :

Gamma-aminobutyric acid receptor subunit beta-3

Gene Full Name :

gamma-aminobutyric acid (GABA) A receptor, beta 3

Synonyms :

ECA5 antibody GABA A receptor beta 3 subunit antibody GABA A receptor subunit beta 3 antibody GABA alpha receptor beta 3 subunit antibody GABA alpha receptor beta-2 subunit antibody GABA(A) receptor beta 3 subunit antibody GABA(A) receptor subunit beta 3 antibody GABA(A) receptor subunit beta-3 antibody GABAA receptor beta 3 subunit antibody GABAA receptor subunit beta 3 antibody GABR B3 antibody GABRB 3 antibody GABRB3 antibody Gamma aminobutyric acid (GABA) A receptor beta 3 antibody Gamma aminobutyric acid A receptor beta 3 antibody Gamma aminobutyric acid receptor subunit beta 3 antibody Gamma-aminobutyric acid receptor subunit beta-3 antibody GBRB3_HUMAN antibody MGC9051 antibody

Uniprot ID :

P28472

more info or order :

Boster Immunoleader product webpage