Anti-EED Antibody | Boster Immunoleader PB9581 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-EED Antibody

catalog :

PB9581

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, rat

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-EED Antibody

Catalog Number :

PB9581

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Polycomb protein EED(EED) detection. Tested with WB in Human;Rat.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, rat

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat

Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E.coli-derived human EED recombinant protein (Position: M256-R441). Human EED shares 100% amino acid (aa) sequence identity with mouse EED.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Polycomb protein EED is a protein that in humans is encoded by the EED gene. It is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin β7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. Furthermore, this protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene.

Reference :

1. "Entrez Gene: EED embryonic ectoderm development". 2. Rietzler M, Bittner M, Kolanus W, Schuster A, Holzmann B (Nov 1998). "The human WD repeat protein WAIT-1 specifically interacts with the cytoplasmic tails of beta7-integrins". J. Biol. Chem. 273 (42): 27459–66. 3. Schumacher A, Lichtarge O, Schwartz S, Magnuson T (Jan 1999). "The murine Polycomb-group gene eed and its human orthologue: functional implications of evolutionary conservation". Genomics 54(1): 79–88.

Gene Name :

EED

Protein Name :

Polycomb protein EED

Gene Full Name :

embryonic ectoderm development

Synonyms :

eed antibody EED protein antibody EED, mouse, homolog of antibody EED_HUMAN antibody Embryonic ectoderm development antibody Embryonic ectoderm development isoform a antibody Embryonic ECTODERM development protein homolog antibody Embryonic ectoderm development protein, mouse, homolog of antibody HEED antibody OTTHUMP00000235483 antibody OTTHUMP00000235484 antibody OTTHUMP00000235485 antibody Polycomb protein eed antibody WAIT 1 antibody WAIT-1 antibody WAIT1 antibody WD protein associating with integrin cytoplasmic tails 1 antibody

Uniprot ID :

O75530

more info or order :

Boster Immunoleader product webpage