Boster Immunoleader

antibody

Anti-RANTES Antibody

PB9573

100 ug/vial

240 USD

polyclonal

rabbit

western blot, ELISA

Anti-RANTES Antibody

PB9573

Polyclonal

Rabbit IgG polyclonal antibody for C-C motif chemokine 5(CCL5) detection. Tested with WB, ELISA in Human.

240 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human

WB,ELISA

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

E. coli-derived human RANTES recombinant protein (Position: Y26-S91). Human RANTES shares 83.3% amino acid (aa) sequence identity with both mouse and rat RANTES.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Chemokine (C-C motif) ligand 5 (also CCL5) is a protein which in humans is encoded by the CCL5 gene. It is also known as RANTES. This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms.

1. Donlon TA, Krensky AM, Wallace MR, Collins FS, Lovett M, Clayberger C (March 1990). "Localization of a human T-cell-specific gene, RANTES (D17S136E), to chromosome 17q11.2-q12". Genomics 6 (3): 548–53. 2. Maghazachi AA, Al-Aoukaty A, Schall TJ (February 1996). "CC chemokines induce the generation of killer cells from CD56+ cells". Eur. J. Immunol. 26 (2): 315–9. 3. Song A, Nikolcheva T, Krensky AM (October 2000). "Transcriptional regulation of RANTES expression in T lymphocytes". Immunol. Rev. 177: 236–45.

CCL5

C-C motif chemokine 5

chemokine (C-C motif) ligand 5

Beta chemokine RANTES precursor antibody CCL 5 antibody CCL5 antibody CCL5_HUMAN antibody Chemokine (C C motif) ligand 5 antibody Chemokine CC Motif Ligand 5 antibody D17S136E antibody EoCP antibody Eosinophil chemotactic cytokine antibody MGC17164 antibody RANTES(4-68) antibody Regulated upon activation normally T expressed and presumably secreted antibody SCYA 5 antibody SCYA5 antibody SIS delta antibody SIS-delta antibody SISd antibody Small inducible cytokine A5 (RANTES) antibody Small inducible cytokine A5 antibody Small inducible cytokine subfamily A (Cys Cys) member 5 antibody Small-inducible cytokine A5 antibody T cell specific protein p288 antibody T cell specific RANTES protein antibody T cell-specific protein P228 antibody T-cell-specific protein RANTES antibody TCP 228 antibody TCP228 antibody

P13501