Anti-CCL4 Antibody | Boster Immunoleader PB9572 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-CCL4 Antibody

catalog :

PB9572

quantity :

100 ug/vial

price :

240 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot, ELISA

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-CCL4 Antibody

Catalog Number :

PB9572

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for C-C motif chemokine 4(CCL4) detection. Tested with WB, ELISA in Human.

Price :

240 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

WB,ELISA

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

ELISA :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

E. coli-derived human CCL4 recombinant protein (Position: A24-N92). Human CCL4 shares 76.8% and 79.7% amino acid (aa) sequence identity with mouse and rat CCL4, respectively.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Chemokine(C-C motif) ligand 4, also known as CCL4, is a protein which in human is encoded by the CCL4 gene. By analysis of somatic cell hybrids and by in situ hybridization, the CCL4 gene was assigned to 17q21-q23. It is a CC chemokine with specificity for CCR5 receptors. And it is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. CCL4 is a major HIV-suppressive factor produced by CD8+ T cells. Performing-low memory CD8+ T cells that normally synthesize CCL4. Based on functional analysis of CCL4, one or more additional beta chemokine receptors that transduce CCL4 signals must also exist. MIP-1alpha and CCL4 have been shown to lack affinity for the erythrocyte surface chemokine receptor/Duffy antigen that binds many alpha as well as beta chemokines(11, 14).

Reference :

1. Bystry RS, Aluvihare V, Welch KA, Kallikourdis M, Betz AG (December 2001). "B cells and professional APCs recruit regulatory T cells via CCL4". Nat. Immunol. 2 (12): 1126–32. 2. Cocchi F, DeVico AL, Garzino-Demo A, Arya SK, Gallo RC, Lusso P (December 1995). Science (journal) 270 (5243): 1811–5. 3. Irving SG, Zipfel PF, Balke J, McBride OW, Morton CC, Burd PR, Siebenlist U, Kelly K (June 1990). Nucleic Acids Res. 18 (11): 3261–70. 4. Kamin-Lewis R, Abdelwahab SF, Trang C, Baker A, DeVico AL, Gallo RC, Lewis GK (July 2001).

Gene Name :

CCL4

Protein Name :

C-C motif chemokine 4

Gene Full Name :

chemokine (C-C motif) ligand 4

Synonyms :

MIP 1 beta antibody Secreted protein G 26 antibody ACT 2 antibody ACT-2 antibody ACT2 antibody AT744.1 antibody AT744.2 antibody C C motif chemokine 4 antibody C C motif chemokine 4 like antibody CC chemokine ligand 4 antibody CC chemokine ligand 4L1d2 antibody CC chemokine ligand 4L2 antibody CCL4 antibody CCL4_HUMAN antibody ccl4l 1 antibody CCL4L antibody CCL4L1 antibody Chemokine (C C motif) ligand 4 antibody Chemokine (C C motif) ligand 4 like 1 antibody Chemokine (C C motif) ligand 4 like 1, telomeric antibody Chemokine (C C motif) ligand 4 like 2 antibody Chemokine CC Motif Ligand 4 antibody G 26 antibody G 26 T lymphocyte secreted protein antibody G-26 T-lymphocyte-secreted protein antibody HC21 antibody LAG 1 antibody LAG-1 antibody LAG1 antibody Lymphocyte activation gene 1 antibody Lymphocyte activation gene 1 protein antibody Macrophage inflammatory protein 1 beta antibody Macrophage inflammatory protein 1-beta antibody Macrophage inflammatory protein 1b2 antibody MGC104418 antibody MGC126025 antibody MGC126026 antibody MIP-1-beta antibody MIP-1-beta(1-69) antibody MIP-1-beta(3-69) antibody MIP1 beta antibody MIP1B antibody MIP1B1 antibody Monocyte adherence induced protein 5 alpha antibody PAT 744 antibody Protein H400 antibody SCYA2 antibody SCYA4 antibody SCYA4L antibody Secreted protein G26 antibody SIS gamma antibody SIS-gamma antibody Small inducible cytokine A4 (homologous to mouse Mip 1b) antibody Small inducible cytokine A4 antibody Small-inducible cytokine A4 antibody T cell activation protein 2 antibody T-cell activation protein 2 antibody

Uniprot ID :

P13236

more info or order :

Boster Immunoleader product webpage