Boster Immunoleader

antibody

Anti-MCP1 Antibody

PB9570

100 ug/vial

240 USD

polyclonal

rabbit

western blot, ELISA

Anti-MCP1 Antibody

PB9570

Polyclonal

Rabbit IgG polyclonal antibody for C-C motif chemokine 2(CCL2) detection. Tested with WB, ELISA in Human.

240 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human

WB,ELISA

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

E. coli-derived human MCP1 recombinant protein (Position: Q24-T99). Human MCP1 shares 60.9% and 59.4% amino acid (aa) sequence identity with mouse and rat MCP1, respectively.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Monocyte chemoattractant protein-1 (MCP-1), a member of the chemokine (chemotactic cytokine) family, is a potent monocyte agonist that is upregulated by oxidized lipids. MCP-1 is also known as CCL2, SCYA2, MCAF. MCAF is a member of family of factors involved in immune and inflammatory responses. The amino acid sequence deduced from the nucleotide sequence reveals the primary structure of the MCAF precursor to be composed of a putative signal peptide sequence of 23 amino acid residues and a mature MCAF sequence of 76 amino acid residues. MCP-1 plays a unique and crucial role in the initiation of atherosclerosis and may provide a new therapeutic target in this disorder. Human MCP-1 is a 8.7KDa non-glycoprotein, consisting of 99 amino acids in precursor form and 76 amino acids in mature form.

1. Furutani, Y.; Nomura, H.; Notake, M.; Oyamada, Y.; Fukui, T.; Yamada, M.; Larsen, C. G.; Oppenheim, J. J.; Matsushima, K. Cloning and sequencing of the cDNA for human monocyte chemotactic and activating factor (MCAF). Biochem. Biophys. 2. Gosling, J.; Slaymaker, S.; Gu, L.; Tseng, S.; Zlot, C. H.; Young, S. G.; Rollins, B. J.; Charo, I. F. MCP-1 deficiency reduces susceptibility to atherosclerosis in mice that overexpress human apolipoprotein B. J. Clin. Invest. 103: 773-778, 1999. 3. Gu, L.; Okaka, Y.; Clinton, S. K.; Gerard, C.; Sukhova, G. K.; Libby, P.; Rollins, B. J. Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice.

CCL2

C-C motif chemokine 2

chemokine (C-C motif) ligand 2

C-C motif chemokine 2 antibody CCL 2 antibody CCL2 antibody CCL2_HUMAN antibody Chemokine (C C motif) ligand 2 antibody Chemokine C C motif ligand 2 antibody Chemokine CC Motif Ligand 2 antibody GDCF 2 antibody GDCF 2 HC11 antibody GDCF-2 antibody GDCF2 antibody HC11 antibody HSMCR30 antibody HSMCR30 antibody JE antibody MCAF antibody MCP 1 antibody MCP-1 antibody MCP1 antibody MGC9434 antibody Monocyte chemoattractant protein 1 antibody Monocyte chemotactic and activating factor antibody Monocyte chemotactic and activating factor antibody Monocyte chemotactic protein 1 antibody Monocyte secretory protein JE antibody SCYA2 antibody Small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig je) antibody Small inducible cytokine A2 antibody Small inducible cytokine subfamily A (Cys Cys), member 2 antibody Small inducible cytokine subfamily A Cys Cys member 2 antibody Small-inducible cytokine A2 antibody SMC CF antibody SMC-CF antibody SMCCF antibody

P13500