Boster Immunoleader

antibody

Anti-Eotaxin Antibody

PB9569

100 ug/vial

240 USD

polyclonal

rabbit

western blot, ELISA

Anti-Eotaxin Antibody

PB9569

Polyclonal

Rabbit IgG polyclonal antibody for Eotaxin(CCL11) detection. Tested with WB, ELISA in Human.

240 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human

WB,ELISA

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

E. coli-derived human Eotaxin recombinant protein (Position: G24-P97). Human Eotaxin shares 61.6% and 63% amino acid (aa) sequence identity with mouse and rat Eotaxin, respectively.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

CCL11 (Chemokine (C-C motif) ligand 11), also known as Eotaxin, is a small cytokine belonging to the CC chemokine family. Eotaxin selectively recruits eosinophils by inducing their chemotaxis, and therefore, is implicated in allergic responses. The effects of Eotaxin are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for which Eotaxin is a ligand include CCR2, CCR3 and CCR5. However, it has been found that eotaxin-1 (CCL11) has high degree selectivity for its receptor, such that they are inactive on neutrophils and monocytes, which do not express CCR3. The gene for human Eotaxin is encoded on three exons and is located on chromosome 17q12.

1. Menzies-Gow, A., Ying, S., Sabroe, I., Stubbs, V. L., Soler, D., Williams, T. J., Kay, A. B.Eotaxin (CCL11) and eotaxin-2 (CCL24) induce recruitment of eosinophils, basophils, neutrophils, and macrophages as well as features of early- and late-phase allergic reactions following cutaneous injection in human atopic and nonatopic volunteers.J. Immun. 169: 2712-2718, 2002. 2. Shin, H. D., Kim, L. H., Park, B. L., Jung, J. H., Kim, J. Y., Chung, I.-Y., Kim, J. S., Lee, J. H., Chung, S. H., Kim, Y. H., Park, H.-S., Choi, J. H., Lee, Y. M., Park, S. W., Choi, B. W., Hong, S.-J., Park, C.-S.Association of eotaxin gene family with asthma and serum total IgE.Hum. Molec. Genet. 12: 1279-1285, 2003. Note: Erratum: Hum. Molec. Genet. 12: 2083 only, 2003. 3. Villeda, S. A., Luo, J., Mosher, K. I., Zou, B., Britschgi, M., Bieri, G., Stan, T. M., Fainberg, N., Ding, Z., Eggel, A., Lucin, K. M., Czirr, E., and 11 others.The ageing systemic milieu negatively regulates neurogenesis and cognitive function.Nature 477: 90-94, 2011.

CCL11

Eotaxin

chemokine (C-C motif) ligand 11

C-C motif chemokine 11 antibody CCL 11 antibody CCL11 antibody CCL11_HUMAN antibody chemokine (C-C motif) ligand 11 antibody Chemokine C C motif ligand 11 antibody Chemokine CC Motif Ligand 11 antibody Chemokine ligand 11 antibody Eosinophil Chemotactic Protein antibody Eotaxin antibody eotaxin-1 antibody MGC22554 antibody SCYA 11 antibody SCYA11 antibody Small inducible cytokine A11 antibody Small inducible cytokine subfamily A (Cys Cys) member 11 antibody small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin) antibody Small inducible cytokine subfamily A member 11 antibody Small-inducible cytokine A11 antibody

P51671