product summary
request information :
company name :
Boster Immunoleader
product type :
antibody
product name :
Anti-Dkk3 Antibody
catalog :
PB9566
quantity :
100 ug/vial
price :
240 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry - paraffin section
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product information
Product Name :
Anti-Dkk3 Antibody
Catalog Number :
PB9566
Clonality :
Polyclonal
Description short :
Rabbit IgG polyclonal antibody for Dickkopf-related protein 3(DKK3) detection. Tested with WB, IHC-P, ELISA in Human;Mouse;Rat.
Price :
240 USD
Ig type :
Rabbit IgG
Size :
100 ug/vial
Form :
Lyophilized
Specificity :
No cross reactivity with other proteins.
Reactivity :
Reacts with: human, mouse, rat
Applications :
WB,IHC-P,ELISA
Western blot :
Concentration: 0.1-0.5μg/ml; Tested Species: Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded S ... :
Concentration: 0.5-1μg/ml; Tested Species: Human, Mouse, Rat
ELISA :
Concentration: 0.1-0.5μg/ml; Tested Species: Human
Notes :
Tested Species: In-house tested species with positive results.
By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections.
Other applications have not been tested.
Optimal dilutions should be determined by end users.
Immunogen :
E. coli-derived human Dkk3 recombinant protein (Position: A22-D152). Human Dkk3 shares 85.5% amino acid (aa) sequence identity with mouse Dkk3.
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purification :
Immunogen affinity purified.
Reconstitution :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage :
At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Relevant detection systems :
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).
Background :
Dickkopf-related protein 3 is a protein that in humans is encoded by the DKK3 gene. This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein.
Reference :
1. "Entrez Gene: DKK3 dickkopf homolog 3 (Xenopus laevis)".
2. Krupnik VE, Sharp JD, Jiang C, Robison K, Chickering TW, Amaravadi L, Brown DE, Guyot D, Mays G, Leiby K, Chang B, Duong T, Goodearl AD, Gearing DP, Sokol SY, McCarthy SA (Dec 1999). "Functional and structural diversity of the human Dickkopf gene family". Gene 238 (2): 301–13.
3. Roman-Gomez J, Jimenez-Velasco A, Agirre X et al. (2004). "Transcriptional silencing of the Dickkopfs-3 (Dkk-3) gene by CpG hypermethylation in acute lymphoblastic leukaemia". Br. J. Cancer 91 (4): 707–13.
Gene Name :
DKK3
Protein Name :
Dickkopf-related protein 3
Gene Full Name :
dickkopf WNT signaling pathway inhibitor 3
Synonyms :
Dickkopf 3 antibody Dickkopf 3 homolog (Xenopus laevis) antibody Dickkopf 3 homolog antibody Dickkopf homolog 3 antibody Dickkopf related protein 3 antibody Dickkopf related protein 3 Precursor antibody Dickkopf WNT signaling pathway inhibitor 3 antibody Dickkopf, Xenopus, homolog of, 3 antibody Dickkopf-3 antibody Dickkopf-related protein 3 antibody Dickkopf3 antibody DKK 3 antibody Dkk-3 antibody DKK3 antibody DKK3_HUMAN antibody hDkk 3 antibody hDkk-3 antibody hDkk3 antibody Regulated in glioma antibody REIC antibody RIG antibody RIG-like 5-6 antibody RIG-like 7-1 antibody
Uniprot ID :
Q9UBP4
more info or order :
company information

Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com925.485.4527
headquarters: USA
Premium Provider of Antibodies and ELISA Kits
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